| Actions en circulation | 26,832,457 shares |
| Actions d'initiés | 1 118 641 shares |
| Participation des initiés | 4,17 % |
| Nombre total d'initiés | 61 |
Indice de confiance des initiés
L'indice de confiance des initiés identifie les entreprises achetées par les initiés.
Il est le résultat d'un modèle quantitatif sophistiqué et multifactoriel qui identifie les entreprises présentant les niveaux les plus élevés de capitalisation d'initiés. Le modèle de notation utilise une combinaison du nombre net d'initiés ayant acheté des actions au cours des 90 derniers jours, du nombre total d'actions achetées en pourcentage du flottant et du nombre total d'actions détenues par les initiés. Le nombre varie de 0 à 100, les chiffres les plus élevés indiquant un niveau d'accumulation supérieur à celui de ses pairs, et 50 étant la moyenne.
Fréquence de mise à jour : Quotidienne
Indice de confiance des dirigeants
L'indice de confiance des dirigeants identifie les entreprises dont les actions sont achetées par des dirigeants d'entreprise.
Par définition, les dirigeants d'entreprise sont des initiés, mais contrairement à d'autres initiés (actionnaires à 10 % et membres du conseil d'administration), les dirigeants travaillent quotidiennement pour l'entreprise et utilisent leur propre argent lorsqu'ils effectuent des opérations (les actionnaires à 10 % et les membres du conseil d'administration sont souvent des gestionnaires de fonds qui gèrent l'argent d'autrui). À ce titre, les opérations d'initiés réalisées par les dirigeants sont beaucoup plus significatives et doivent être traitées de manière appropriée.
Comme l'indice de confiance des initiés, l'indice de confiance des dirigeants est le résultat d'un modèle quantitatif sophistiqué et multifactoriel qui identifie les entreprises présentant les niveaux les plus élevés d'accumulation de dirigeants.
Fréquence de mise à jour : Quotidienne
Principaux indicateurs des initiés
Cette carte montre comment l'entreprise se positionne par rapport à divers indicateurs d'initiés. La position en centile montre comment cette entreprise se situe par rapport aux autres entreprises sur les marchés américains. Une position plus élevée indique une meilleure situation.
Par exemple, il est généralement admis que les achats d'initiés sont un indicateur positif, de sorte que les entreprises dont les achats d'initiés sont plus nombreux se positionnent mieux que celles dont les achats d'initiés sont moins nombreux (ou même les ventes d'initiés).
Pourcentage du flottant acheté par les initiés (position)
0.000 %( )
1266 out of 11220Le pourcentage du flottant acheté par les initiés est le nombre total d'actions achetées par les initiés moins le nombre total d'actions vendues par les initiés au cours des 90 derniers jours, divisé par le flottant total et multiplié par 100.
Graphique des opérations d'initiés
Les opérations d'initiés de Syros Pharmaceuticals, Inc. sont présentées dans le graphique suivant. Les initiés sont des dirigeants, des administrateurs ou des investisseurs importants dans une entreprise. En général, il est illégal pour les initiés d'effectuer des opérations d'initiés dans leur entreprise sur la base d'informations matérielles non publiques. Cela ne signifie pas qu'il est illégal pour eux d'effectuer toute transaction dans leurs propres entreprises. Toutefois, ils doivent déclarer toutes les transactions à la SEC au moyen d'un formulaire 4.
Liste d'initiés et indicateurs de rentabilité
Ce tableau présente la liste des initiés connus et est généré automatiquement à partir des dépôts communiqués à la SEC. Outre les noms, le titre le plus récent et la désignation du directeur, du dirigeant ou du propriétaire à 10 %, nous indiquons les dernières participations divulguées. En outre, lorsque cela est possible, nous indiquons les performances historiques des opérations d'initiés. La performance historique des transactions est une moyenne pondérée de la performance des opérations d'achat réelles sur le marché public effectuées par l'initié. Pour plus d'informations sur le mode de calcul, regardez ce webinaire sur YouTube.
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| Initié | Profit moyen (%) | Actions détenues |
Fractionnement Ajusté |
|---|---|---|---|
|
Noubar Afeyan
10% Owner -
|
0 | 0 | |
|
Aisling Capital Iii Lp
10% Owner -
|
908 565 | 90 856 | |
| Srinivas Akkaraju Director - [D] | 9 333 | 9 333 | |
|
ARCH Venture Partners VII, L.P.
10% Owner -
|
4 242 051 | 424 205 | |
|
ARCH Venture Partners VII, LLC
10% Owner -
|
4 242 051 | 424 205 | |
|
Aisling Capital Partners III LLC
10% Owner -
|
908 565 | 90 856 | |
|
Aisling Capital Partners III LP
10% Owner -
|
908 565 | 90 856 | |
| Mark J Alles Director - [D] | 3 666 | 3 666 | |
|
Arch Venture Fund VII LP
10% Owner -
|
4 242 051 | 424 205 | |
| Michael W Bonney | 11 000 | ||
|
Clinton Bybee
10% Owner -
|
4 242 051 | 424 205 | |
| Stephane Bancel Director - [D] | 47 980 | 4 798 | |
|
Keith Crandell
10% Owner -
|
4 242 051 | 424 205 | |
| Conley Chee President & CEO, Director - [D] [O] | 0 | 0 | |
|
Management Co Deerfield
10% Owner -
|
628 566 | 62 857 | |
| Colleen Elizabeth DeSimone Principal Accounting Officer - [O] | 0 | 0 | |
|
Deerfield Mgmt III, L.P.
10% Owner -
|
628 566 | 62 857 | |
|
Deerfield Mgmt L.P.
10% Owner -
|
628 566 | 62 857 | |
|
Deerfield Private Design Fund III, L.P.
10% Owner -
|
628 566 | 62 857 | |
|
Deerfield Special Situations Fund, L.P.
10% Owner -
|
628 566 | 62 857 |
| Initié | Profit moyen (%) | Actions détenues |
Fractionnement Ajusté |
|---|---|---|---|
| Deborah Dunsire Director - [D] | 12 000 | 12 000 | |
|
Steve Elms
10% Owner -
|
908 565 | 90 856 | |
| Sue Gail Eckhardt Director - [D] | 16 000 | 16 000 | |
| Marsha Fanucci Director - [D] | 16 000 | 16 000 | |
| Joseph J Jr Ferra Chief Financial Officer - [O] | 87 000 | 8 700 | |
|
Flagship VentureLabs IV, LLC
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV General Partner LLC
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV, L.P.
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV-Rx, L.P.
10% Owner -
|
0 | 0 | |
|
James E Flynn
10% Owner -
|
628 566 | 62 857 | |
|
Nathanael Gray
10% Owner -
|
853 332 | 85 333 | |
|
Jeremy Green
10% Owner -
|
49 793 | 4 979 | |
| Jason Haas Chief Financial Officer - [O] | 0 | 0 | |
|
JEB Syros Trust
10% Owner -
|
703 332 | 70 333 | |
|
Edwin M Jr Kania
10% Owner -
|
0 | 0 | |
| Kuvalanka Kyle D. | 78 000 | ||
|
Robert Nelsen
10% Owner -
|
4 242 051 | 424 205 | |
|
Amir Nashat
Director, 10% Owner -
[D]
|
48 320 | 4 832 | |
| Oh Andrew M. Director - [D] | 16 000 | 16 000 | |
| Eric R Olson Chief Scientific Officer - [O] | 6 661 | 6 661 |
| Initié | Profit moyen (%) | Actions détenues |
Fractionnement Ajusté |
|---|---|---|---|
| Sanj K Patel | 11 000 | ||
|
Perspecta Trust LLC
10% Owner -
|
703 332 | 70 333 | |
|
Polaris Entrepreneurs' Fund VII, L.P.
10% Owner -
|
48 320 | 4 832 | |
|
Polaris Management Co. VII, L.L.C.
10% Owner -
|
48 320 | 4 832 | |
|
Polaris Partners VII, L.P.
10% Owner -
|
48 320 | 4 832 | |
|
Dennis J Purcell
10% Owner -
|
908 565 | 90 856 | |
| Gerald E Quirk Chief Legal & Compliance Offic - [O] | 0 | 0 | |
|
Redmile Group, LLC
10% Owner -
|
49 793 | 4 979 | |
| David Roth Chief Medical Officer - [O] | 0 | 0 | |
| Vicki L Sato | 11 000 | ||
|
Andrew N Schiff
10% Owner -
|
908 565 | 90 856 | |
| Philip A Sharp Director - [D] | 40 000 | 4 000 | |
| Alice Tsang Shaw | 22 000 | ||
| Nancy A Simonian Director - [D] | 4 000 | 4 000 | |
| Springhorn Jeremy P. Chief Business Officer - [O] | 35 000 | 3 500 | |
| Kristin Stephens Chief Development Officer - [O] | 0 | 0 | |
| Timothy Tyson Director - [D] | 33 189 | 33 189 | |
| Peter Wirth Director - [D] | 16 000 | 16 000 | |
|
WuXi Healthcare Ventures II, L.P.
10% Owner -
|
423 805 | 42 380 | |
|
WuXi PharmTech Healthcare Fund I L.P.
10% Owner -
|
931 857 | 93 186 | |
| Richard A Young Director - [D] | 10 667 | 10 667 |
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Historique des achats d'initiés - Analyse des bénéfices à court terme
Dans cette section, nous analysons la rentabilité de chaque achat d'initié non planifié et effectué sur le marché public dans SYRS / Syros Pharmaceuticals, Inc.. Cette analyse permet de comprendre si l'initié génère régulièrement des rendements anormaux et s'il vaut la peine d'être suivi. Cette analyse porte sur l'année qui suit chaque transaction et les résultats sont théoriques .
Le tableau suivant présente les achats sur le marché public les plus récents qui ne faisaient pas partie d'un plan de trading automatique.
Prix ajusté est le prix ajusté suite au fractionnement. Actions ajustées est le nombre d'actions ajustées suite au fractionnement.
Historique des ventes d'initiés - Analyse des pertes à court terme
Dans cette section, nous analysons l'évitement des pertes à court terme de chaque vente d'initié non planifiée et réalisée sur le marché public dans SYRS / Syros Pharmaceuticals, Inc.. Un schéma cohérent d'évitement des pertes peut suggérer que les transactions de vente futures peuvent prédire des baisses de prix. Cette analyse porte sur l'année qui suit chaque transaction, et les résultats sont théoriques .
Le tableau suivant présente les ventes les plus récentes sur le marché public qui ne faisaient pas partie d'un plan de trading automatique.
Prix ajusté est le prix ajusté suite au fractionnement. Actions ajustées est le nombre d'actions ajustées suite au fractionnement.
Historique des transactions
Click the link icon to see the full transaction history. Transactions reported as part of a 10b5-1 automatic trading plan will have an X in the column marked 10b-5.
| Date de dépôt |
Date de transaction |
Formulaire | Initié | Libellé | Nom du titre | Code | Direct | Prix d'exercice |
Prix unitaire |
Unités Modifié |
Valeur Modifiée (1K) |
Options restantes |
Actions restantes |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-12-04 | 2024-12-02 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 0,2702 | -37 070 | -10 | 4 000 | ||||
| 2024-11-27 | 2024-11-25 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 0,2653 | -134 713 | -36 | 41 070 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Haas Jason | SYRS | Common Stock | D | 0,2103 | -137 803 | -29 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Chee Conley | SYRS | Common Stock | D | 0,1998 | -134 797 | -27 | 0 | ||||
| 2024-11-20 | 2024-11-19 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 0,2212 | -46 657 | -10 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Stephens Kristin | SYRS | Common Stock | D | 0,2200 | -36 133 | -8 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Roth David | SYRS | Common Stock | D | 0,1969 | -12 099 | -2 | 0 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 40 125 | 175 783 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2,0900 | -8 707 | -18 | 130 797 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 17 000 | 139 504 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Roth David | SYRS | Common Stock | D | 2,0900 | -6 776 | -14 | 12 099 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Roth David | SYRS | Common Stock | D | 18 875 | 18 875 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2,0900 | -5 624 | -12 | 137 803 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 18 875 | 143 427 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,0900 | -6 104 | -13 | 36 133 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 17 000 | 42 237 | ||||||
| 2024-10-02 | 2024-09-30 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 2,1000 | -3 100 | -7 | 46 657 | ||||
| 2024-10-02 | 2024-09-30 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 10 000 | 49 757 | ||||||
| 2024-09-18 | 2024-09-16 | 4 | Young Richard A | SYRS | Common Stock | D | 2 667 | 10 667 | ||||||
| 2024-09-18 | 2024-09-16 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 2 667 | 9 333 | ||||||
| 2024-09-12 | 2024-09-11 | 4 | Chee Conley | SYRS | Common Stock | D | 1,7084 | 50 000 | 85 | 122 504 | ||||
| 2024-09-12 | 2024-09-10 | 4 | Chee Conley | SYRS | Common Stock | D | 1,5052 | 50 000 | 75 | 72 504 | ||||
| 2024-09-12 | 2024-09-12 | 4 | Haas Jason | SYRS | Common Stock | D | 1,6762 | 45 344 | 76 | 124 552 | ||||
| 2024-09-12 | 2024-09-11 | 4 | Haas Jason | SYRS | Common Stock | D | 1,5781 | 19 293 | 30 | 79 208 | ||||
| 2024-09-12 | 2024-09-10 | 4 | Haas Jason | SYRS | Common Stock | D | 1,5493 | 35 363 | 55 | 59 915 | ||||
| 2024-07-02 | 2024-06-28 | 4 | Young Richard A | SYRS | Common Stock | D | 5,1200 | -34 837 | -178 | 8 000 | ||||
| 2024-06-07 | 2024-06-05 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 4 000 | 16 000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 4 000 | 135 658 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | WIRTH PETER | SYRS | Common Stock | D | 4 000 | 16 000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 4 000 | 16 000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 4 000 | 16 000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 4 000 | 33 189 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Young Richard A | SYRS | Common Stock | D | 4 000 | 42 837 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Dunsire Deborah | SYRS | Common Stock | D | 4 000 | 12 000 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 4 000 | 6 666 | ||||||
| 2024-04-05 | 2024-04-03 | 4 | Roth David | SYRS | Common Stock | D | 4,9500 | -10 451 | -52 | 0 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 5,1200 | -4 218 | -22 | 25 237 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 11 666 | 29 455 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2 000 | 17 789 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 5,1200 | -14 052 | -72 | 131 658 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 39 566 | 145 710 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 6 000 | 106 144 | ||||||
| 2024-04-02 | 2024-04-02 | 4 | Roth David | SYRS | Common Stock | D | 4,9803 | -150 | -1 | 10 451 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Roth David | SYRS | Common Stock | D | 5,1200 | -4 732 | -24 | 10 601 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Roth David | SYRS | Common Stock | D | 13 333 | 15 333 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Roth David | SYRS | Common Stock | D | 2 000 | 2 000 | ||||||
| 2024-04-02 | 2024-03-28 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 5,5900 | -7 046 | -39 | 39 757 | ||||
| 2024-04-02 | 2024-03-27 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 22 500 | 46 803 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Haas Jason | SYRS | Common Stock | D | 5,1200 | -4 732 | -24 | 24 552 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 13 333 | 29 284 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2 000 | 15 951 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Chee Conley | SYRS | Common Stock | D | 5,1200 | -3 500 | -18 | 22 504 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 11 666 | 26 004 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2 000 | 14 338 | ||||||
| 2023-12-26 | 2023-12-21 | 4 | AKKARAJU SRINIVAS By Samsara BioCapital, L.P. | SYRS | Common Stock | I | 4,4200 | 904 977 | 4 000 | 1 786 427 | ||||
| 2023-12-14 | 2023-12-12 | 4 | Roth David | SYRS | Common Stock | D | 4,9500 | -6 287 | -31 | 0 | ||||
| 2023-12-08 | 2023-12-06 | 4 | Roth David | SYRS | Common Stock | D | 3,9500 | -6 287 | -25 | 6 287 | ||||
| 2023-11-02 | 2023-11-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 2,2200 | -13 401 | -30 | 100 144 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 40 125 | 113 545 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Haas Jason | SYRS | Common Stock | D | 2,2200 | -6 301 | -14 | 13 951 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 18 875 | 20 252 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,2200 | -5 676 | -13 | 15 789 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 17 000 | 21 465 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Roth David | SYRS | Common Stock | D | 2,2200 | -6 301 | -14 | 12 574 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Roth David | SYRS | Common Stock | D | 18 875 | 18 875 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Chee Conley | SYRS | Common Stock | D | 2,2200 | -6 004 | -13 | 12 338 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 17 000 | 18 342 | ||||||
| 2023-10-20 | 2023-10-19 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 2,1000 | -6 897 | -14 | 24 303 | ||||
| 2023-10-20 | 2023-10-11 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 22 500 | 31 200 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | Young Richard A | SYRS | Common Stock | D | 2 666 | 38 837 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 2 666 | 2 666 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | Alles Mark J | SYRS | Common Stock | D | 2 666 | 3 666 | ||||||
| 2023-08-02 | 2023-07-31 | 4 | Roth David | SYRS | Common Stock | D | 3,9500 | -7 348 | -29 | 0 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 3,5000 | -689 | -2 | 6 661 | ||||
| 2023-06-02 | 2023-06-01 | 4 | WIRTH PETER | SYRS | Common Stock | D | 4 000 | 12 000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Young Richard A | SYRS | Common Stock | D | 4 000 | 36 171 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 4 000 | 12 000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 4 000 | 29 189 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 4 000 | 12 000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 4 000 | 12 000 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | TYSON TIMOTHY | SYRS | Common Stock | D | 257 | 8 257 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | TYSON TIMOTHY | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 691 489 | 881 450 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Chee Conley | SYRS | Common Stock | D | 2,5800 | -658 | -2 | 1 342 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2 000 | 2 000 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Olson Eric R | SYRS | Common Stock | D | 2,5800 | -623 | -2 | 7 350 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Olson Eric R | SYRS | Common Stock | D | 2 000 | 7 973 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,5800 | -623 | -2 | 4 465 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2 000 | 5 088 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 2,5800 | -1 852 | -5 | 73 420 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 6 000 | 75 272 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Haas Jason | SYRS | Common Stock | D | 2,5800 | -623 | -2 | 1 377 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2 000 | 2 000 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Roth David | SYRS | Common Stock | D | 2,5800 | -623 | -2 | 7 348 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Roth David | SYRS | Common Stock | D | 2 000 | 7 971 | ||||||
| 2022-10-13 | 3 | Quirk Gerald E | SYRS | Common Stock | D | 8 700 | ||||||||
| 2022-10-03 | 2022-09-30 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 6,3704 | 14 000 | 89 | 24 932 | ||||
| 2022-10-03 | 2022-09-29 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 5,7196 | 2 932 | 17 | 10 932 | ||||
| 2022-09-19 | 2022-09-16 | 4 | WIRTH PETER | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Dunsire Deborah | SYRS | Common Stock | D | 8 000 | 8 000 | ||||||
| 2022-04-04 | 2022-04-01 | 4 | Roth David | SYRS | Common Stock | D | 1,1200 | -27 281 | -31 | 59 719 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 1,1200 | -14 115 | -16 | 30 885 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 1,1200 | -58 883 | -66 | 692 723 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Olson Eric R | SYRS | Common Stock | D | 1,1200 | -27 266 | -31 | 59 734 | ||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Restricted Stock Units | D | 400 000 | 400 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Restricted Stock Units | D | 240 000 | 240 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1,59 | 375 000 | 375 000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Restricted Stock Units | D | 200 000 | 200 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Restricted Stock Units | D | 80 000 | 80 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 1,59 | 125 000 | 125 000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Restricted Stock Units | D | 200 000 | 200 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Restricted Stock Units | D | 80 000 | 80 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1,59 | 100 000 | 100 000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Restricted Stock Units | D | 200 000 | 200 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Restricted Stock Units | D | 80 000 | 80 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Stock Option (right to buy) | D | 1,59 | 100 000 | 100 000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Haas Jason | SYRS | Restricted Stock Units | D | 80 000 | 80 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Haas Jason | SYRS | Stock Option (right to buy) | D | 1,59 | 125 000 | 125 000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Chee Conley | SYRS | Restricted Stock Units | D | 80 000 | 80 000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Chee Conley | SYRS | Stock Option (right to buy) | D | 1,59 | 100 000 | 100 000 | |||||
| 2022-01-06 | 2022-01-05 | 4 | Olson Eric R | SYRS | Common Stock | D | 3,4669 | -2 208 | -8 | 0 | ||||
| 2021-10-13 | 2021-10-12 | 4 | Haas Jason | SYRS | Stock Option (right to buy) | D | 4,54 | 750 000 | 750 000 | |||||
| 2021-09-28 | 2021-09-27 | 4 | Chee Conley | SYRS | Stock Option (right to buy) | D | 4,81 | 360 000 | 360 000 | |||||
| 2021-09-10 | 2021-09-09 | 4 | Dunsire Deborah | SYRS | Stock Option (right to buy) | D | 5,28 | 35 000 | 35 000 | |||||
| 2021-07-01 | 2021-07-01 | 4 | Olson Eric R | SYRS | Common Stock | D | 5,5500 | -1 164 | -6 | 0 | ||||
| 2021-06-10 | 2021-06-08 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Eckhardt Sue Gail | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 6,30 | 17 500 | 17 500 | |||||
| 2021-06-10 | 3 | Stephens Kristin | SYRS | Common Stock | D | 45 000 | ||||||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1,01 | -3 628 | 90 697 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Common Stock | D | 9,4740 | -3 628 | -34 | 0 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Common Stock | D | 1,0100 | 3 628 | 4 | 3 628 | ||||
| 2021-02-19 | 2021-02-17 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11,41 | 94 000 | 94 000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 11,41 | 94 000 | 94 000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 11,41 | 94 000 | 94 000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 11,41 | 119 000 | 119 000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 11,41 | 119 000 | 119 000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 11,41 | 304 000 | 304 000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | Young Richard A | SYRS | Common Stock | D | 12,0500 | -3 750 | -45 | 321 711 | ||||
| 2021-02-10 | 2020-11-17 | 4/A | Young Richard A | SYRS | Common Stock | D | 8,7500 | -5 357 | -47 | 329 211 | ||||
| 2021-02-10 | 2020-11-16 | 4/A | Young Richard A | SYRS | Common Stock | D | 8,9800 | -633 | -6 | 334 568 | ||||
| 2021-02-10 | 2021-02-08 | 4 | Young Richard A | SYRS | Common Stock | D | 13,0400 | -3 750 | -49 | 325 461 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10,09 | -4 988 | 280 012 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 8,51 | -14 168 | 79 165 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3,04 | -10 761 | 21 524 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 10,0900 | 4 988 | 50 | 563 606 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 8,5100 | 14 168 | 121 | 558 618 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3,0400 | 10 761 | 33 | 544 450 | ||||
| 2020-12-11 | 2020-12-08 | 4 | AKKARAJU SRINIVAS | SYRS | Warrants (right to buy) | I | 11,00 | 156 250 | 156 250 | |||||
| 2020-12-11 | 2020-12-08 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 625 000 | 1 899 616 | ||||||
| 2020-11-18 | 2020-11-17 | 4 | Young Richard A | SYRS | Common Stock | D | 8,7500 | -5 357 | -47 | 339 211 | ||||
| 2020-11-18 | 2020-11-16 | 4 | Young Richard A | SYRS | Common Stock | D | 8,9800 | -633 | -6 | 344 568 | ||||
| 2020-10-19 | 2020-10-19 | 4 | Young Richard A | SYRS | Common Stock | D | 8,7500 | -5 673 | -50 | 335 201 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8,7500 | -317 | -3 | 340 874 | ||||
| 2020-09-16 | 2020-09-15 | 4 | Young Richard A | SYRS | Common Stock | D | 10,3900 | -5 990 | -62 | 341 191 | ||||
| 2020-09-09 | 2020-09-08 | 4 | Eckhardt Sue Gail | SYRS | Stock Option (right to buy) | D | 8,94 | 35 000 | 35 000 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Young Richard A | SYRS | Common Stock | D | 12,5900 | -5 990 | -75 | 347 181 | ||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1,01 | -10 787 | 94 325 | |||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 13,0000 | -10 787 | -140 | 0 | ||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 1,0100 | 10 787 | 11 | 10 787 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1,01 | -4 963 | 105 112 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 13,0000 | -4 963 | -65 | 0 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 1,0100 | 4 963 | 5 | 4 963 | ||||
| 2020-08-19 | 2020-08-18 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 13,0955 | -158 583 | -2 077 | 1 274 616 | ||||
| 2020-08-19 | 2020-08-17 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 13,0000 | -744 | -10 | 1 433 199 | ||||
| 2020-07-17 | 2020-07-15 | 4 | Young Richard A | SYRS | Common Stock | D | 11,8500 | -5 990 | -71 | 353 171 | ||||
| 2020-07-07 | 2020-07-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 11,7162 | -1 753 | -21 | 0 | ||||
| 2020-07-06 | 2020-07-01 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11,0149 | -4 627 | -51 | 1 433 943 | ||||
| 2020-06-25 | 2020-06-25 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11,1484 | -54 972 | -613 | 1 438 570 | ||||
| 2020-06-25 | 2020-06-24 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11,0669 | -48 775 | -540 | 1 493 542 | ||||
| 2020-06-25 | 2020-06-23 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11,1069 | -50 953 | -566 | 1 542 317 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8,7500 | -5 990 | -52 | 359 161 | ||||
| 2020-06-11 | 2020-06-11 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 9,17 | 17 500 | 17 500 | |||||
| 2020-05-15 | 2020-05-15 | 4 | Young Richard A | SYRS | Common Stock | D | 9,2224 | -5 990 | -55 | 365 151 | ||||
| 2020-05-13 | 2020-05-13 | 4 | Alles Mark J | SYRS | Common Stock | D | 8,8590 | 10 000 | 89 | 10 000 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8,7500 | -23 960 | -210 | 371 141 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 7,3818 | -1 446 | -11 | 0 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 7,54 | 294 000 | 294 000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 7,54 | 94 000 | 94 000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 7,54 | 94 000 | 94 000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 7,54 | 94 000 | 94 000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 7,54 | 94 000 | 94 000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 7,54 | 94 000 | 94 000 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3,04 | -8 210 | 1 018 123 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3,04 | -10 762 | 1 026 333 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3,04 | -33 429 | 1 037 095 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3,0400 | 52 401 | 159 | 533 689 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 6,22 | 35 000 | 35 000 | |||||
| 2019-11-12 | 2019-11-12 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 4,9667 | 10 121 | 50 | 35 000 | ||||
| 2019-11-12 | 2019-11-11 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 4,9932 | 9 879 | 49 | 24 879 | ||||
| 2019-08-19 | 2019-08-16 | 4 | Young Richard A | SYRS | Common Stock | D | 10,0000 | -22 700 | -227 | 395 101 | ||||
| 2019-08-19 | 2019-08-15 | 4 | Young Richard A | SYRS | Common Stock | D | 10,0000 | -2 300 | -23 | 417 801 | ||||
| 2019-07-17 | 2019-07-17 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7,6964 | -34 521 | -266 | 4 242 051 | ||||
| 2019-07-17 | 2019-07-16 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7,8078 | -25 779 | -201 | 4 276 572 | ||||
| 2019-07-17 | 2019-07-15 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8,2651 | -2 700 | -22 | 4 302 051 | ||||
| 2019-06-12 | 2019-06-11 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Shaw Alice Tsang | SYRS | Stock Option (right to buy) | D | 5,60 | 22 000 | 22 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | BONNEY MICHAEL W | SYRS | Stock Option (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Fanucci Marsha | SYRS | Common Stock (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | SATO VICKI L | SYRS | Common Stock (right to buy) | D | 5,60 | 11 000 | 11 000 | |||||
| 2019-04-11 | 2019-04-09 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock Warrants (rights to buy) | I | 8,62 | 133 333 | 133 333 | |||||
| 2019-04-11 | 2019-04-09 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 7,5000 | 533 332 | 4 000 | 1 593 270 | ||||
| 2019-03-14 | 2019-03-14 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8,1498 | -43 000 | -350 | 4 305 051 | ||||
| 2019-03-14 | 2019-03-13 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8,1993 | -2 820 | -23 | 4 348 051 | ||||
| 2019-03-14 | 2019-03-13 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7,8862 | -81 591 | -643 | 4 350 871 | ||||
| 2019-03-14 | 2019-03-12 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7,3674 | -40 092 | -295 | 4 432 462 | ||||
| 2019-03-11 | 2019-03-11 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6,4924 | -44 878 | -291 | 4 472 554 | ||||
| 2019-03-11 | 2019-03-08 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6,9266 | -84 496 | -585 | 4 517 432 | ||||
| 2019-03-11 | 2019-03-07 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6,8736 | -35 209 | -242 | 4 601 928 | ||||
| 2019-02-14 | 2019-02-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 6,71 | 75 000 | 75 000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Ferra Joseph J Jr | SYRS | Common Stock | D | 87 000 | 87 000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 6,71 | 75 000 | 75 000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Olson Eric R | SYRS | Common Stock | D | 87 000 | 87 000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 6,71 | 75 000 | 75 000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 87 000 | 87 000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 6,71 | 75 000 | 75 000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Roth David | SYRS | Common Stock | D | 87 000 | 87 000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 6,71 | 285 000 | 285 000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 188 000 | 669 288 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 6,71 | 75 000 | 75 000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 87 000 | 102 000 | ||||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3,04 | 12 084 | 785 523 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1,01 | 75 050 | 797 607 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1,01 | 23 454 | 872 657 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3,0400 | 12 084 | 37 | 481 288 | ||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 1,0100 | 98 504 | 99 | 469 204 | ||||
| 2018-06-15 | 2018-06-14 | 4 | BONNEY MICHAEL W | SYRS | Stock Option (right to buy) | D | 12,95 | 13 000 | 13 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 12,95 | 11 000 | 11 000 | |||||
| 2018-03-12 | 2018-03-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 12,32 | 50 000 | 50 000 | |||||
| 2018-03-12 | 2018-03-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 12,32 | 150 000 | 150 000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 10,09 | 75 000 | 75 000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 13,30 | 11 666 | 11 666 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 10,09 | 75 000 | 75 000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10,09 | 285 000 | 285 000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 10,09 | 75 000 | 75 000 | |||||
| 2018-02-13 | 2017-09-08 | 5 | AFEYAN NOUBAR | SYRS | Common Stock | D | -24 527 | 0 | ||||||
| 2018-02-02 | 2018-01-31 | 4 | AKKARAJU SRINIVAS see footnote 1 | SYRS | Common Stock | I | 9,5500 | 209 424 | 2 000 | 1 059 938 | ||||
| 2017-12-22 | 3/A | AKKARAJU SRINIVAS By Samsara BioCapital, L.P. | SYRS | Common Stock | I | 740 740 | ||||||||
| 2017-12-15 | 2017-12-15 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 9,0840 | 15 000 | 136 | 15 000 | ||||
| 2017-12-14 | 2017-12-14 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 8,9900 | 26 600 | 239 | 830 494 | ||||
| 2017-12-14 | 2017-12-13 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 8,9700 | 68 400 | 614 | 803 894 | ||||
| 2017-12-14 | 2017-12-12 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 9,4000 | 14 774 | 139 | 735 494 | ||||
| 2017-11-14 | 2017-11-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11,65 | 50 000 | 50 000 | |||||
| 2017-11-14 | 2017-11-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11,65 | 150 000 | 150 000 | |||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Stock Option (right to buy) | D | 3,04 | -550 | 13 016 | |||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Common Stock | D | 16,0605 | -550 | -9 | 0 | ||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Common Stock | D | 3,0400 | 550 | 2 | 550 | ||||
| 2017-09-22 | 2017-06-08 | 4/A | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 14,62 | 22 000 | 22 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Nashat Amir | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Young Richard A | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 14,62 | 11 000 | 11 000 | |||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | -54 293 | 0 | ||||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | -306 222 | 612 442 | ||||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | D | -1 295 997 | 2 378 663 | ||||||
| 2017-08-16 | 2017-08-14 | 4 | Young Richard A | SYRS | Common Stock | D | 22,0000 | -3 282 | -72 | 420 101 | ||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1,01 | 2 500 | 110 075 | |||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 23,5876 | -2 500 | -59 | 0 | ||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 1,0100 | 2 500 | 3 | 2 500 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Young Richard A | SYRS | Common Stock | D | 22,0889 | -3 282 | -72 | 423 383 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1,01 | 12 500 | 25 025 | |||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Common Stock | D | 21,8500 | -12 500 | -273 | 0 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Common Stock | D | 1,0100 | 12 500 | 13 | 12 500 | ||||
| 2017-06-12 | 3 | AKKARAJU SRINIVAS by Samsara BioCapital, L.P. | SYRS | Common Stock | I | 1 441 440 | ||||||||
| 2017-06-12 | 3 | AKKARAJU SRINIVAS by Samsara BioCapital, L.P. | SYRS | Common Stock | I | 1 441 440 | ||||||||
| 2017-06-12 | 2017-06-08 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 14,26 | 11 000 | 11 000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 14,26 | 22 000 | 22 000 | |||||
| 2017-02-13 | 2017-02-09 | 5 | Young Richard A | SYRS | Common Stock | D | -106 667 | 426 665 | ||||||
| 2017-02-13 | 2017-02-10 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 10,90 | 63 500 | 63 500 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 10,90 | 40 000 | 40 000 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 10,90 | 63 500 | 63 500 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10,90 | 175 000 | 175 000 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Kuvalanka Kyle D. | SYRS | Stock Option (right to buy) | D | 10,90 | 78 000 | 78 000 | |||||
| 2017-01-30 | 2017-01-27 | 4 | WIRTH PETER | SYRS | Stock Option (Right to Buy) | D | 10,76 | 22 000 | 22 000 | |||||
| 2016-09-29 | 2016-09-27 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 13,30 | 105 000 | 105 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Bancel Stephane | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-09-19 | 2016-09-16 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 12,17 | 75 000 | 75 000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 12,59 | 22 000 | 22 000 | |||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series B Preferred Stock | D | -1 589 269 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-3 Preferred Stock | D | -7 500 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-2 Preferred Stock | D | -5 000 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-1 Preferred Stock | D | -1 000 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 12,5000 | 400 000 | 5 000 | 4 637 137 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 423 805 | 4 237 137 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 2 000 000 | 3 813 332 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 1 333 333 | 1 813 332 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 266 666 | 479 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Series B Preferred Stock | I | -83 129 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Series B Preferred Stock | I | -4 366 825 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 12,5000 | 26 153 | 327 | 48 320 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 12,5000 | 373 847 | 4 673 | 1 538 333 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 22 167 | 22 167 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 1 164 486 | 1 164 486 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series B Preferred Stock | I | -444 995 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series B Preferred Stock | I | -1 779 981 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-3 Preferred Stock | I | -1 500 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-3 Preferred Stock | I | -6 000 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-2 Preferred Stock | I | -1 000 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-2 Preferred Stock | I | -4 000 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-1 Preferred Stock | I | -200 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-1 Preferred Stock | I | -800 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 12,5000 | 80 000 | 1 000 | 918 664 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 12,5000 | 320 000 | 4 000 | 3 674 660 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 118 665 | 838 664 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 474 661 | 3 354 660 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 400 000 | 719 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 1 600 000 | 2 879 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 266 666 | 319 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 1 066 666 | 1 279 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 53 333 | 53 333 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 213 333 | 213 333 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -151 576 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -117 931 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -982 762 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -178 074 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -317 853 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12,5000 | 9 373 | 117 | 49 793 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12,5000 | 174 320 | 2 179 | 205 767 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12,5000 | 104 670 | 1 308 | 366 739 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12,5000 | 144 383 | 1 805 | 191 869 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 40 420 | 40 420 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 31 447 | 31 447 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 262 069 | 262 069 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 47 486 | 47 486 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 84 760 | 84 760 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series B Preferred Stock | D | -1 994 471 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-3 Preferred Stock | D | -500 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-1 Preferred Stock | D | -500 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-2 Preferred Stock | D | -500 000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 531 858 | 931 857 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133 333 | 399 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133 333 | 399 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133 333 | 399 999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Series B Preferred Stock | I | -83 129 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Series B Preferred Stock | I | -4 366 825 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 12,5000 | 26 153 | 327 | 48 320 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 12,5000 | 373 847 | 4 673 | 1 538 333 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 22 167 | 22 167 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 1 164 486 | 1 164 486 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Series B Preferred Stock | D | -1 907 122 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Common Stock | D | 12,5000 | 400 000 | 5 000 | 908 565 | ||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Common Stock | D | 508 565 | 508 565 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series B Preferred Stock | I | -1 589 269 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-3 Preferred Stock | I | -7 500 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-2 Preferred Stock | I | -5 000 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-1 Preferred Stock | I | -1 000 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 12,5000 | 400 000 | 5 000 | 4 637 137 | ||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 423 805 | 4 237 137 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 2 000 000 | 3 813 332 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 1 333 333 | 1 813 332 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 266 666 | 479 999 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Simonian Nancy A | SYRS | Series A-2 Preferred Stock | D | -250 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 66 666 | 370 702 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | D | -550 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40 000 | 40 000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40 000 | 40 000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40 000 | 40 000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | D | 146 666 | 146 666 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Bancel Stephane | SYRS | Series A-2 Preferred Stock | D | -100 000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Bancel Stephane | SYRS | Common Stock | D | 26 666 | 47 980 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Series B Convertible Preferred Stock | I | -508 566 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Series B Convertible Preferred Stock | I | -1 186 654 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Common Stock | I | 12,5000 | 120 000 | 1 500 | 628 566 | ||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Common Stock | I | 12,5000 | 280 000 | 3 500 | 1 466 654 | ||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Common Stock | I | 508 566 | 508 566 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Common Stock | I | 1 186 654 | 1 186 654 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | WuXi Healthcare Ventures II, L.P. | SYRS | Series B Preferred Stock | D | -1 589 269 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | WuXi Healthcare Ventures II, L.P. | SYRS | Common Stock | D | 423 805 | 423 805 | ||||||
| 2016-06-29 | 3 | Gray Nathanael | SYRS | Common Stock | D | 853 332 | ||||||||
| 2016-06-29 | 3 | Gray Nathanael | SYRS | Common Stock | D | 853 332 | ||||||||
| 2016-06-29 | 3 | JEB Syros Trust | SYRS | Common Stock | D | 703 332 | ||||||||
| 2016-06-29 | 3 | JEB Syros Trust | SYRS | Common Stock | D | 703 332 | ||||||||
| 2016-06-29 | 3 | Bancel Stephane | SYRS | Common Stock | D | 42 628 | ||||||||
| 2016-06-29 | 3 | Bancel Stephane | SYRS | Common Stock | D | 42 628 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A | SYRS | Common Stock | D | 768 072 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o William H. Cole | SYRS | Common Stock | I | 544 036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o Bennett H. Cole | SYRS | Common Stock | I | 544 036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o William H. Cole | SYRS | Common Stock | I | 544 036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o Bennett H. Cole | SYRS | Common Stock | I | 544 036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A | SYRS | Common Stock | D | 768 072 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426 664 | ||||||||
| 2016-06-29 | 3 | NELSEN ROBERT Shares held by ARCH Venture Fund VII, L.P. | SYRS | Common Stock | I | 426 666 | ||||||||
| 2016-06-29 | 3 | NELSEN ROBERT Shares held by ARCH Venture Fund VII, L.P. | SYRS | Common Stock | I | 426 666 | ||||||||
| 2016-06-29 | 3 | Perspecta Trust LLC Owned by the JEB Syros Trust, of which Perspecta Trust LLC is trustee. | SYRS | Common Stock | I | 703 332 | ||||||||
| 2016-06-29 | 3 | Perspecta Trust LLC Owned by the JEB Syros Trust, of which Perspecta Trust LLC is trustee. | SYRS | Common Stock | I | 703 332 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426 666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426 666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426 666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426 666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426 666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426 666 | ||||||||
| 2016-06-29 | 3 | Young Richard A | SYRS | Common Stock | D | 1 066 664 | ||||||||
| 2016-06-29 | 3 | Young Richard A | SYRS | Common Stock | D | 1 066 664 |
P
Achat sur le marché public ou privé d'un titre non dérivé ou dérivé
S
Vente sur le marché public ou privé d'un titre non dérivé ou dérivé
A
Attribution, récompense ou autre acquisition de titres de l'entreprise (comme une option).
C
Conversion d'un produit dérivé
D
Vente ou transfert de titres à l'entreprise
F
Paiement du prix d'exercice ou de la dette fiscale en utilisant une partie des titres reçus de l'entreprise
G
Don de titres par ou à l'initié
K
Swaps d'actions et opérations de couverture similaires
M
Exercice ou conversion d'un titre dérivé reçu de l'entreprise (tel qu'une option)
V
Une transaction déclarée volontairement sur le formulaire 4
J
Autre (accompagnée d'une note de bas de page décrivant la transaction)
