TNGNQ / Tengion, Inc. - Documents déposés auprès de la SEC, rapport annuel, procuration

Tengion, Inc.
US ˙ OTCPK

Statistiques de base
CIK 1296391
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Tengion, Inc.
SEC Filings (Chronological Order)
Cette page fournit une liste complète et chronologique des documents déposés auprès de la SEC, à l'exclusion des documents relatifs à la participation que nous fournissons ailleurs.
February 11, 2021 SC 13G/A

Tengion, Inc.

SC 13G/A 1 tngnq13ga.htm TNGNQ SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Tengion, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 88034G208 (CUSIP Number) December 31, 2020 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to desi

February 16, 2016 SC 13G/A

TNGNQ / Tengion, Inc. / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

February 12, 2016 SC 13G/A

TNGNQ / Tengion, Inc. / CAPITAL VENTURES INTERNATIONAL - SC 13G/A Passive Investment

SC 13G/A 1 a16-372632sc13ga.htm SC 13G/A CUSIP No. 880346109 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. 3)* Tengion, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Se

October 2, 2015 SC 13G

TNGNQ / Tengion, Inc. / CVI Investments, Inc. - SC 13G Passive Investment

SC 13G 1 a15-205493sc13g.htm SC 13G CUSIP No. 88034G208 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. )* Tengion, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securiti

February 17, 2015 SC 13G/A

TNGNQ / Tengion, Inc. / QVT Financial LP - SCHEDULE 13G/A Passive Investment

Schedule 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Tengion Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 88034G208 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate

February 17, 2015 SC 13G/A

TNGNQ / Tengion, Inc. / RA Capital Management, LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Tengion Inc. (Name of Issuer) Common Stock, par value, $0.001 per share (Title of Class of Securities) 88034G208 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule purs

February 17, 2015 SC 13G/A

TNGNQ / Tengion, Inc. / Flynn James E Passive Investment

SC 13G/A 1 e613314sc13ga-tengion.htm SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 3) * Tengion, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 88034G208 (CUSIP Number) December 31, 2014

February 13, 2015 SC 13G/A

TNGNQ / Tengion, Inc. / CAPITAL VENTURES INTERNATIONAL - SC 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. 2)* Tengion, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 880346109 (CUSIP Number) December 31, 2014 (Date of

February 13, 2015 SC 13G/A

TNGNQ / Tengion, Inc. / CELGENE CORP /DE/ - AMENDMENT NO. 2 TO SCHEDULE 13G Passive Investment

SC 13G/A 1 d874034dsc13ga.htm AMENDMENT NO. 2 TO SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 2)* TENGION, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 88034G109 (CUSIP Number) December 31, 2014 (Date of Event Which Requires Filing of this S

February 11, 2015 SC 13D/A

TNGNQ / Tengion, Inc. / HEALTHCAP IV LP - SCHEDULE 13D/A Activist Investment

SC 13D/A 1 d869067dsc13da.htm SCHEDULE 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 4)* Tengion, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 88034G 10 9 (CUSIP Number) HealthCap IV, L.P. 18 Avenue d’Ouchy Lausanne, V8 CH-1006 With a copy to: Martin J. Waters Wilson Sonsini G

December 29, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 33 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 33 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

December 29, 2014 8-K

Triggering Events That Accelerate or Increase a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement, Bankruptcy or Receivership, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 22, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. E

December 29, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 21 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 21 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

December 29, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 33 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 33 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

December 5, 2014 EX-10.1

Tengion, Inc. Amended and Restated Management Severance Pay Plan Instrument of Amendment and Termination, dated December 4, 2014

Exhibit 10.1 TENGION, INC. AMENDED AND RESTATED MANAGEMENT SEVERANCE PAY PLAN Instrument of Amendment and Termination WHEREAS, Tengion, Inc. (the “Company”) maintains the Tengion, Inc. Amended and Restated Management Severance Pay Plan (the “Management Severance Plan”), effective as of March 15, 2012; and WHEREAS, the Company as settlor of the Management Severance Plan wishes to amend and terminat

December 5, 2014 EX-10.4

Amendment to Offer Letter, as amended, to Timothy Bertram, dated December 4, 2014

EX-10.4 5 ex10-4.htm EXHIBIT 10.4 Exhibit 10.4 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 Timothy A. Bertram c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 28, 2004, as amended December 22, 2008 Dear Tim: This letter agreement (the “Amendment”) amen

December 5, 2014 EX-10.4

Amendment to Offer Letter, as amended, to Timothy Bertram, dated December 4, 2014

Exhibit 10.4 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 Timothy A. Bertram c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 28, 2004, as amended December 22, 2008 Dear Tim: This letter agreement (the “Amendment”) amends the offer letter between you an

December 5, 2014 EX-10.1

Tengion, Inc. Amended and Restated Management Severance Pay Plan Instrument of Amendment and Termination, dated December 4, 2014

EX-10.1 2 ex10-1.htm EXHIBIT 10.1 Exhibit 10.1 TENGION, INC. AMENDED AND RESTATED MANAGEMENT SEVERANCE PAY PLAN Instrument of Amendment and Termination WHEREAS, Tengion, Inc. (the “Company”) maintains the Tengion, Inc. Amended and Restated Management Severance Pay Plan (the “Management Severance Plan”), effective as of March 15, 2012; and WHEREAS, the Company as settlor of the Management Severance

December 5, 2014 EX-10.2

Amendment to Amended Employment Agreement, as amended, with John L. Miclot, dated December 4, 2014

Exhibit 10.2 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 John L. Miclot c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Amended Employment Agreement dated January 20, 2012, as amended December 5, 2013 Dear John: This letter agreement (the “Amendment”) amends the Amended Empl

December 5, 2014 EX-10.4

Amendment to Offer Letter, as amended, to Timothy Bertram, dated December 4, 2014

Exhibit 10.4 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 Timothy A. Bertram c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 28, 2004, as amended December 22, 2008 Dear Tim: This letter agreement (the “Amendment”) amends the offer letter between you an

December 5, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 20 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 20 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

December 5, 2014 EX-10.2

Amendment to Amended Employment Agreement, as amended, with John L. Miclot, dated December 4, 2014

Exhibit 10.2 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 John L. Miclot c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Amended Employment Agreement dated January 20, 2012, as amended December 5, 2013 Dear John: This letter agreement (the “Amendment”) amends the Amended Empl

December 5, 2014 EX-10.3

Amendment to Offer Letter, as amended, to A. Brian Davis, dated December 4, 2014

Exhibit 10.3 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 A. Brian Davis c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 29, 2010, as amended January 1, 2013 Dear Brian: This letter agreement (the “Amendment”) amends the offer letter between you and Te

December 5, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 32 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 32 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

December 5, 2014 EX-10.2

Amendment to Amended Employment Agreement, as amended, with John L. Miclot, dated December 4, 2014

Exhibit 10.2 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 John L. Miclot c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Amended Employment Agreement dated January 20, 2012, as amended December 5, 2013 Dear John: This letter agreement (the “Amendment”) amends the Amended Empl

December 5, 2014 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Financial Statements and Exhibits, Costs Associated with Exit or Disposal Activities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 1, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Em

December 5, 2014 EX-10.3

Amendment to Offer Letter, as amended, to A. Brian Davis, dated December 4, 2014

Exhibit 10.3 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 A. Brian Davis c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 29, 2010, as amended January 1, 2013 Dear Brian: This letter agreement (the “Amendment”) amends the offer letter between you and Te

December 5, 2014 EX-10.3

Amendment to Offer Letter, as amended, to A. Brian Davis, dated December 4, 2014

Exhibit 10.3 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 A. Brian Davis c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 29, 2010, as amended January 1, 2013 Dear Brian: This letter agreement (the “Amendment”) amends the offer letter between you and Te

December 5, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 32 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 32 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

December 5, 2014 EX-10.4

Amendment to Offer Letter, as amended, to Timothy Bertram, dated December 4, 2014

Exhibit 10.4 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 Timothy A. Bertram c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 28, 2004, as amended December 22, 2008 Dear Tim: This letter agreement (the “Amendment”) amends the offer letter between you an

December 5, 2014 EX-10.1

Tengion, Inc. Amended and Restated Management Severance Pay Plan Instrument of Amendment and Termination, dated December 4, 2014

EX-10.1 2 ex10-1.htm EXHIBIT 10.1 Exhibit 10.1 TENGION, INC. AMENDED AND RESTATED MANAGEMENT SEVERANCE PAY PLAN Instrument of Amendment and Termination WHEREAS, Tengion, Inc. (the “Company”) maintains the Tengion, Inc. Amended and Restated Management Severance Pay Plan (the “Management Severance Plan”), effective as of March 15, 2012; and WHEREAS, the Company as settlor of the Management Severance

December 5, 2014 EX-10.3

Amendment to Offer Letter, as amended, to A. Brian Davis, dated December 4, 2014

Exhibit 10.3 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 A. Brian Davis c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Offer Letter dated July 29, 2010, as amended January 1, 2013 Dear Brian: This letter agreement (the “Amendment”) amends the offer letter between you and Te

December 5, 2014 EX-10.1

Tengion, Inc. Amended and Restated Management Severance Pay Plan Instrument of Amendment and Termination, dated December 4, 2014

Exhibit 10.1 TENGION, INC. AMENDED AND RESTATED MANAGEMENT SEVERANCE PAY PLAN Instrument of Amendment and Termination WHEREAS, Tengion, Inc. (the “Company”) maintains the Tengion, Inc. Amended and Restated Management Severance Pay Plan (the “Management Severance Plan”), effective as of March 15, 2012; and WHEREAS, the Company as settlor of the Management Severance Plan wishes to amend and terminat

December 5, 2014 EX-10.2

Amendment to Amended Employment Agreement, as amended, with John L. Miclot, dated December 4, 2014

Exhibit 10.2 Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 4, 2014 tel: (336) 722-5855 fax: (336) 722-2436 John L. Miclot c/o Tengion Inc. 3929 Westpoint Blvd, Suite G Winston-Salem, NC 27103 Subject: Amendment to Amended Employment Agreement dated January 20, 2012, as amended December 5, 2013 Dear John: This letter agreement (the “Amendment”) amends the Amended Empl

December 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2014 EX-99.2

A. Brian Davis

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among

December 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among

December 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among

December 3, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 31 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 31 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

December 3, 2014 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 2, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Em

December 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among

December 3, 2014 EX-99.1

A. Brian Davis

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 31 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 31 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

December 3, 2014 424B3

2,298,412 Shares Tengion, Inc.

424B3 1 tengion424b3.htm TENGION, INC. FORM 424(B)(3) 333-190196 Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 19 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 19 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part

November 21, 2014 DEF 14A

TNGNQ / Tengion, Inc. DEF 14A - - TENGION, INC. FORM DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant þ Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement þ Definitive Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)

November 14, 2014 EX-99.1

Press release issued November 14, 2014 providing Clinical Update and reporting Third Quarter 2014 Financial Results and Cash Position

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Provides Clinical Update and Reports Third Quarter 2014 Financial Results and Cash Position WINSTON-SALEM, NC, November 14, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported key clinical data along with financial and operating results for the quarter ended September 30, 2014.

November 14, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 14, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. E

November 14, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 29 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 29 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

November 14, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 17 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 17 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

November 14, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 30 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 30 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

November 14, 2014 EX-99

Press release issued November 14, 2014 providing Clinical Update and reporting Third Quarter 2014 Financial Results and Cash Position

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Provides Clinical Update and Reports Third Quarter 2014 Financial Results and Cash Position WINSTON-SALEM, NC, November 14, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported key clinical data along with financial and operating results for the quarter ended September 30, 2014.

November 14, 2014 EX-99.1

Press release issued November 14, 2014 providing Clinical Update and reporting Third Quarter 2014 Financial Results and Cash Position

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Provides Clinical Update and Reports Third Quarter 2014 Financial Results and Cash Position WINSTON-SALEM, NC, November 14, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported key clinical data along with financial and operating results for the quarter ended September 30, 2014.

November 14, 2014 10-Q

Tengion TENGION, INC. FORM 10-Q (Quarterly Report)

tengion10q.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) [X] QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2014 OR [ ] TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file numb

November 14, 2014 EX-99.1

Tengion Provides Clinical Update and Reports Third Quarter 2014 Financial Results and Cash Position

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Provides Clinical Update and Reports Third Quarter 2014 Financial Results and Cash Position WINSTON-SALEM, NC, November 14, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported key clinical data along with financial and operating results for the quarter ended September 30, 2014.

November 14, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 30 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 30 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

November 14, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 18 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 18 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

November 14, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 29 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 29 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

November 10, 2014 PRE 14A

TNGNQ / Tengion, Inc. PRE 14A - - TENGION, INC. FORM PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant þ Filed by a Party other than the Registrant ¨ Check the appropriate box: þ Preliminary Proxy Statement ¨ Definitive Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)

October 1, 2014 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 28 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 28 supplements the prospectus dated March 28, 2013

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 28 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 28 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

October 1, 2014 8-K

Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 1, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Emp

October 1, 2014 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 16 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 16 supplements the prospectus dated September

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 16 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 16 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

October 1, 2014 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 28 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 28 supplements the prospectus dated March 28, 20

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 28 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 28 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

September 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated September 2, 2014

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended on Februa

September 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated September 2, 2014

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended on Februa

September 3, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 27 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 27 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

September 3, 2014 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 2, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. E

September 3, 2014 EX-99.2

A. Brian Davis

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Tengion, Inc

September 3, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 15 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 15 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

September 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated September 2, 2014

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Tengion, Inc

September 3, 2014 EX-99.1

A. Brian Davis

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended on Februa

September 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated September 2, 2014

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Tengion, Inc

September 3, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 27 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 27 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

September 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated September 2, 2014

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Tengion, Inc

September 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated September 2, 2014

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 September 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended on Februa

August 14, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-34688 Tengion, In

August 14, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 26 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 26 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

August 14, 2014 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 26 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 26 supplements the prospectus dated March 28, 20

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 26 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 26 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

August 14, 2014 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 14 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 14 supplements the prospectus dated September

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 14 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 14 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

July 1, 2014 8-K

Unregistered Sales of Equity Securities

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 1, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Employ

July 1, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 13 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 13 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

July 1, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 25 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 25 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

July 1, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 25 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 25 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

June 3, 2014 8-K

Financial Statements and Exhibits, Other Events - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 2, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Employ

June 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated June 2, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Teng

June 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated June 2, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Teng

June 3, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 24 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 24 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

June 3, 2014 EX-99.2

A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Teng

June 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated June 2, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended o

June 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated June 2, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended o

June 3, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 12 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 12 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

June 3, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 24 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 24 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

June 3, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated June 2, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Teng

June 3, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated June 2, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended o

June 3, 2014 EX-99.1

A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance June 2, 2014 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended o

May 15, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 23 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 23 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

May 15, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 11 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 11 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

May 15, 2014 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-34688 Tengion, I

May 15, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 23 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 23 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

May 8, 2014 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 10 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 10 supplements the prospectus dated September

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 10 (To Prospectus dated September 18, 2013, as amended) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 10 supplements the prospectus dated September 18, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement

May 8, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 22 (To Prospectus dated March 28, 2013, as amended) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 22 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 33

May 8, 2014 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 2, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Employe

May 8, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 22 (To Prospectus dated March 28, 2013, as amended) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 22 supplements the prospectus dated March 28, 2013 (as supplemented or amended to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-1

April 9, 2014 POS AM

- TENGION, INC. FORM POS AM 333-190196

As filed with the Securities and Exchange Commission on April 9, 2014 Registration No.

April 9, 2014 POS AM

- TENGION, INC. FORM POS AM 333-186687

As filed with the Securities and Exchange Commission on April 9, 2014 Registration No.

April 9, 2014 POS AM

- TENGION, INC. FORM POS AM 333-184761

As filed with the Securities and Exchange Commission on April 9, 2014 Registration No.

April 1, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 21 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 21 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

April 1, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 9 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 9 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

April 1, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 21 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 21 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

April 1, 2014 8-K

Unregistered Sales of Equity Securities - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 1, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Emplo

March 27, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 24, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Empl

March 27, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 20 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 20 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

March 27, 2014 EX-99.1

Tengion, Inc. Press Release, dated March 26, 2014, reporting Fourth Quarter and Full Year 2013 Financial Results

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Reports Fourth Quarter and Full Year 2013 Financial Results WINSTON-SALEM, NC, March 26, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported its financial results for the fourth quarter and full year ended December 31, 2013 and provided a business update. “We made important pro

March 27, 2014 EX-99.1

Tengion Reports Fourth Quarter and Full Year 2013 Financial Results

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Reports Fourth Quarter and Full Year 2013 Financial Results WINSTON-SALEM, NC, March 26, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported its financial results for the fourth quarter and full year ended December 31, 2013 and provided a business update. “We made important pro

March 27, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 20 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 20 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

March 27, 2014 EX-99.1

Tengion Reports Fourth Quarter and Full Year 2013 Financial Results

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Reports Fourth Quarter and Full Year 2013 Financial Results WINSTON-SALEM, NC, March 26, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported its financial results for the fourth quarter and full year ended December 31, 2013 and provided a business update. “We made important pro

March 27, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 8 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 8 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

March 27, 2014 EX-99.1

Tengion, Inc. Press Release, dated March 26, 2014, reporting Fourth Quarter and Full Year 2013 Financial Results

Investor and Media Contact: A. Brian Davis [email protected] 336.201.0155 Tengion Reports Fourth Quarter and Full Year 2013 Financial Results WINSTON-SALEM, NC, March 26, 2014 - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today reported its financial results for the fourth quarter and full year ended December 31, 2013 and provided a business update. “We made important pro

March 26, 2014 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-34688 Tengion, Inc. (

March 26, 2014 DEF 14A

- TENGION, INC. FORM DEF 14A

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant o Check the appropriate box: o Preliminary Proxy Statement o Confidential, For Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) x Definitive Proxy Statement o Definitive Additional Materials o Soliciting Material Pursuant to Rule 14a-11(c) or rule 14a-12 TENGION, INC.

March 4, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 19 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 19 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

March 4, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated March 3, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Ten

March 4, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated March 3, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended

March 4, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated March 3, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended

March 4, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 7 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 7 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

March 4, 2014 EX-99.2

Sincerely,

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Ten

March 4, 2014 8-K

Financial Statements and Exhibits, Other Events - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 3, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Emplo

March 4, 2014 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated March 3, 2014

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended

March 4, 2014 EX-99.1

Sincerely,

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amended

March 4, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 19 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 19 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

March 4, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated March 3, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Ten

March 4, 2014 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated March 3, 2014

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 March 3, 2014 tel: (336) 201-0155 fax: (336) 722-2436 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and among Ten

February 26, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 18 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 18 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

February 26, 2014 EX-3.1

Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of Tengion, Inc.

CERTIFICATE OF AMENDMENT TO THE FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF TENGION, INC.

February 26, 2014 EX-3.1

Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of Tengion, Inc.

CERTIFICATE OF AMENDMENT TO THE FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF TENGION, INC.

February 26, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 18 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 18 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

February 26, 2014 EX-3.1

Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of Tengion, Inc.

CERTIFICATE OF AMENDMENT TO THE FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF TENGION, INC.

February 26, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 6 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 6 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

February 26, 2014 EX-3.1

Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of Tengion, Inc.

CERTIFICATE OF AMENDMENT TO THE FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF TENGION, INC.

February 26, 2014 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 24, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. E

February 14, 2014 SC 13D/A

TNGNQ / Tengion, Inc. / HEALTHCAP IV LP - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 3)* Tengion, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 88034G 10 9 (CUSIP Number) HealthCap IV, L.P. 18 Avenue d’Ouchy Lausanne, V8 CH-1006 With a copy to: Martin J. Waters Wilson Sonsini Goodrich & Rosati Professional Corpor

February 14, 2014 SC 13G/A

TNGNQ / Tengion, Inc. / QVT Financial LP - SCHEDULE 13G AMENDMENT NO. 1 Passive Investment

Schedule 13G Amendment No. 1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Tengion Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 88034G208 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate bo

February 14, 2014 SC 13G/A

TNGNQ / Tengion, Inc. / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

February 14, 2014 SC 13G/A

TNGNQ / Tengion, Inc. / RA Capital Management, LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Tengion Inc. (Name of Issuer) Common Stock, par value, $0.001 per share (Title of Class of Securities) 88034G208 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule purs

February 13, 2014 SC 13G/A

TNGNQ / Tengion, Inc. / CAPITAL VENTURES INTERNATIONAL - SC 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. 1)* Tengion, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 880346109 (CUSIP Number) December 31, 2013 (Date of

February 12, 2014 SC 13G/A

TNGNQ / Tengion, Inc. / CELGENE CORP /DE/ - SC 13G/A Passive Investment

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* TENGION, INC. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 88034G109 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the

February 11, 2014 SC 13G/A

TNGNQ / Tengion, Inc. / OAK MANAGEMENT CORP Passive Investment

Converted by EDGARwiz UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

January 27, 2014 DEF 14A

- TENGION, INC. FORM DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant þ Filed by a Party other than the Registrant ¨ Check the appropriate box: o Preliminary Proxy Statement þ Definitive Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)

January 27, 2014 CORRESP

-

January 27, 2014 Lisa M. Kahle T +1 (415) 315-6320 F +1 (415) 315-6033 [email protected] Via EDGAR and E-Mail Jeffrey P. Riedler Assistant Director U.S. Securities and Exchange Commission 100 F Street, N.E. Washington, D.C. 20549 Re: Tengion, Inc. Preliminary Proxy Statement on Schedule 14A Filed on January 15, 2014 File No. 001-34688 Dear Mr. Riedler: On behalf of Tengion, Inc. (“Tengion”

January 15, 2014 PRE 14A

- TENGION, INC. FORM PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 14A PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 Filed by the Registrant þ Filed by a Party other than the Registrant ¨ Check the appropriate box: þ Preliminary Proxy Statement ¨ Definitive Proxy Statement ¨ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)

January 14, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 17 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 17 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

January 14, 2014 EX-99.1

Corporate Presentation January 2014 Certain statements in this presentation may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements relate to our future plans, objectives,

Corporate Presentation January 2014 Certain statements in this presentation may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.

January 14, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Em

January 14, 2014 EX-99.1

Investor Presentation

Corporate Presentation January 2014 Certain statements in this presentation may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.

January 14, 2014 EX-99.1

Investor Presentation

Corporate Presentation January 2014 Certain statements in this presentation may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.

January 14, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 17 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 17 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

January 14, 2014 EX-99.1

Investor Presentation

Corporate Presentation January 2014 Certain statements in this presentation may constitute forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995.

January 14, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 5 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 5 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

January 2, 2014 8-K

Unregistered Sales of Equity Securities - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 2, 2014 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Emp

January 2, 2014 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 16 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 16 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

January 2, 2014 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 16 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 16 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

January 2, 2014 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 4 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 4 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

December 9, 2013 SC 13D/A

TNGNQ / Tengion, Inc. / Medtronic Inc - SCHEDULE 13D AMENDMENT NO. 2 Activist Investment

Schedule 13D Amendment No. 2 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) Under the Securities Exchange Act of 1934 (Amendment No. 2)* Tengion, Inc. (Name of Issuer) Common Stock, $.001 par value (Title of Class of

December 3, 2013 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 3 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 3 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

December 3, 2013 EX-99.2

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax:

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and betwee

December 3, 2013 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated December 2, 2013

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and betwee

December 3, 2013 8-K

Financial Statements and Exhibits, Other Events - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 2, 2013 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Em

December 3, 2013 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 15 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 15 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

December 3, 2013 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated December 2, 2013

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and betwee

December 3, 2013 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2013

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2013 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 15 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 15 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

December 3, 2013 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2013

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2013 EX-99.1

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax:

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2013 EX-99.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated December 2, 2013

Exhibit 99.1 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012 and as amend

December 3, 2013 EX-99.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated December 2, 2013

Exhibit 99.2 A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 December 2, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) tel: (336) 201-0155 fax: (336) 722-2436 [email protected] Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and betwee

December 2, 2013 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 2 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 2 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

December 2, 2013 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 14 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 14 supplements the prospectus dated March 28, 2013 (as suppl

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 14 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 14 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

December 2, 2013 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 14 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 14 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

December 2, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-34688 Tengio

November 15, 2013 NT 10-Q

- TENGION, INC. FORM 12B-25

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING SEC FILE NUMBER 001-34688 CUSIP NUMBER 88034G208 (Check one): o Form 10-K o Form 20-F o Form 11-K x Form 10-Q o Form 10-D o Form N-SAR o Form N-CSR For Period Ended: September 30, 2013 o Transition Report on Form 10-K o Transition Report on Form 20-F o Transition Report on Form 11-K o Tr

October 2, 2013 8-K

Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Other Events - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2013 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S.

October 2, 2013 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 13 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 13 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

October 2, 2013 EX-10.1

Celgene Corporation Waiver, dated September 26, 2013

Exhibit 10.1 CELGENE CORPORATION WAIVER This WAIVER, dated as of September 26, 2013, is made by Celgene Corporation (the “Corporation”). Reference is made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2013, that are held by the Corporation (the “Warrants”). Reference is also made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2

October 2, 2013 EX-10.1

Celgene Corporation Waiver, dated September 26, 2013

Exhibit 10.1 CELGENE CORPORATION WAIVER This WAIVER, dated as of September 26, 2013, is made by Celgene Corporation (the “Corporation”). Reference is made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2013, that are held by the Corporation (the “Warrants”). Reference is also made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2

October 2, 2013 424B3

2,298,412 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-190196 PROSPECTUS SUPPLEMENT NO. 1 (To Prospectus dated September 18, 2013) 2,298,412 Shares Tengion, Inc. This Prospectus Supplement No. 1 supplements the prospectus dated September 18, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-190196). The Pro

October 2, 2013 EX-10.1

Celgene Corporation Waiver, dated September 26, 2013

Exhibit 10.1 CELGENE CORPORATION WAIVER This WAIVER, dated as of September 26, 2013, is made by Celgene Corporation (the “Corporation”). Reference is made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2013, that are held by the Corporation (the “Warrants”). Reference is also made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2

October 2, 2013 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 13 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 13 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

October 2, 2013 EX-10.1

Celgene Corporation Waiver, dated September 26, 2013

Exhibit 10.1 CELGENE CORPORATION WAIVER This WAIVER, dated as of September 26, 2013, is made by Celgene Corporation (the “Corporation”). Reference is made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2013, that are held by the Corporation (the “Warrants”). Reference is also made to those Warrants to Purchase Common Stock of Tengion, Inc., dated as of June 28, 2

September 16, 2013 CORRESP

-

September 16, 2013 VIA EDGAR TRANSMISSION Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

August 30, 2013 CORRESP

-

Lisa M. Kahle T +1 (415) 315-6320 F +1 (415) 315-6033 [email protected] August 30, 2013 Securities and Exchange Commission Division of Corporation Finance 100 F. Street, N.E. Washington, DC 20549 Attn: Jeffrey P. Riedler Re: Tengion, Inc. Registration Statement on Form S-1 Filed July 26, 2013 File No. 333-190196 Dear Mr. Riedler: On behalf of Tengion, Inc. (the “Company”), we are responding

August 30, 2013 S-1/A

- TENGION, INC. FORM S-1A

As filed with the Securities and Exchange Commission on August 30, 2013 Registration No.

August 21, 2013 EX-10.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated August 20, 2013

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] August 20, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012, as amended on February 14

August 21, 2013 EX-10.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated August 20, 2013

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] August 20, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012, as amended on February 14

August 21, 2013 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 12 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 12 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

August 21, 2013 EX-10.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated August 20, 2013

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] August 20, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and between Tengion, Inc

August 21, 2013 EX-10.1

Share Issuance Notice delivered to the holders of senior secured notes issued on October 2, 2012, dated August 20, 2013

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] August 20, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated October 2, 2012, as amended on February 14

August 21, 2013 EX-10.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated August 20, 2013

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] August 20, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and between Tengion, Inc

August 21, 2013 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 12 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 12 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

August 21, 2013 8-K

Financial Statements and Exhibits, Other Events - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 20, 2013 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Emp

August 21, 2013 EX-10.2

Share Issuance Notice delivered to the holders of senior secured notes issued on June 28, 2013, dated August 20, 2013

A. Brian Davis Chief Financial Officer Senior Vice President, Finance Tengion, Inc. 3929 Westpoint Blvd., Suite G Winston-Salem, NC 27103 tel: (336) 201-0155 fax: (336) 722-2436 [email protected] August 20, 2013 Re: Notice of Intent to Issue Stock for Interest Payment (via e-mail) Dear Lenders, Pursuant to Section 2.9 of the Facility Agreement dated June 28, 2013, by and between Tengion, Inc

August 15, 2013 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 11 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 11 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

August 15, 2013 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 11 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 11 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

August 14, 2013 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended June 30, 2013 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 001-34688 Tengion, Inc. (Exac

August 8, 2013 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 10 (To Prospectus dated March 28, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 10 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospect

August 8, 2013 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 7, 2013 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Empl

August 8, 2013 EX-99.1

Tengion Announces Promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance

Press Release Tengion Announces Promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance WINSTON-SALEM, N.C., Aug. 7, 2013 /PRNewswire/ - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today announced the promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance. Mr. Davis has served as Chief Financial Officer of Ten

August 8, 2013 424B3

592,000 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 10 (To Prospectus dated March 28, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 10 supplements the prospectus dated March 28, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus

August 8, 2013 EX-99.1

Press Release, dated August 7, 2013

Press Release Tengion Announces Promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance WINSTON-SALEM, N.C., Aug. 7, 2013 /PRNewswire/ - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today announced the promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance. Mr. Davis has served as Chief Financial Officer of Ten

August 8, 2013 EX-99.1

Tengion Announces Promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance

Press Release Tengion Announces Promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance WINSTON-SALEM, N.C., Aug. 7, 2013 /PRNewswire/ - Tengion, Inc. (OTCQB: TNGN), a leader in regenerative medicine, today announced the promotion of A. Brian Davis to Chief Financial Officer and Senior Vice President, Finance. Mr. Davis has served as Chief Financial Officer of Ten

July 26, 2013 S-1

Registration Statement - TENGION, INC. FORM S-1

As filed with the Securities and Exchange Commission on July 26, 2013 Registration No.

July 19, 2013 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 9 (To Prospectus dated March 26, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 9 supplements the prospectus dated March 26, 2013 (as supplem

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 9 (To Prospectus dated March 26, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 9 supplements the prospectus dated March 26, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospectus

July 19, 2013 424B3

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 9 (To Prospectus dated March 26, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 9 supplements the prospectus dated March 26, 2013 (as supplement

Filed Pursuant to Rule 424(b)(3) Registration No. 333-184761 PROSPECTUS SUPPLEMENT NO. 9 (To Prospectus dated March 26, 2013) 592,000 Shares Tengion, Inc. This Prospectus Supplement No. 9 supplements the prospectus dated March 26, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-184761). The Prospectus an

July 19, 2013 8-K

Submission of Matters to a Vote of Security Holders

8-K 1 tengion8k.htm TENGION, INC. FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 15, 2013 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (S

July 12, 2013 SC 13G

TNGNQ / Tengion, Inc. / RA CAPITAL MANAGEMENT, L.P. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.)* Tengion Inc. (Name of Issuer) Common Stock, par value, $0.001 per share (Title of Class of Securities) 88034G208 (CUSIP Number) June 28, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant t

July 8, 2013 SC 13G

TNGNQ / Tengion, Inc. / QVT Financial LP - SCHEDULE 13G Passive Investment

Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Tengion Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 88034G208 (CUSIP Number) June 28, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the ru

July 8, 2013 SC 13G

TNGNQ / Tengion, Inc. / CAPITAL VENTURES INTERNATIONAL - SC 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2. (Amendment No. )* Tengion, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 880346109 (CUSIP Number) June 28, 2013 (Date of Even

July 5, 2013 EX-4.2

Form of Warrants issued to various investors on June 28, 2013

Exhibit 4.2 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAW, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS S

July 5, 2013 EX-4.1

Form of Senior Secured Convertible Notes issued to various investors on June 28, 2013

Exhibit 4.1 THIS NOTE IS BEING ISSUED WITH ORIGINAL ISSUE DISCOUNT (“OID”), IN THE AMOUNT TO BE DETERMINED BY THE COMPANY AND WHICH WILL BE PROVIDED TO EACH HOLDER IN ACCORDANCE WITH APPLICABLE REGULATIONS. THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE SOLD, TRANSF

July 5, 2013 EX-10.6

Collaboration and Option Agreement by and among Tengion, Inc., Celgene Corporation and Celgene European Investment Company LLC, dated June 28, 2013

Exhibit 10.6 COLLABORATION AND OPTION AGREEMENT by and between TENGION, INC., CELGENE CORPORATION and CELGENE EUROPEAN INVESTMENT COMPANY LLC June 28, 2013 COLLABORATION AND OPTION AGREEMENT This Collaboration and Option Agreement (this “Agreement”) dated the 28th day of June, 2013 (the “Effective Date”) is by and among Tengion, Inc., a Delaware corporation having its principal office at 3929 West

July 5, 2013 EX-10.5

Amendment, Waiver and Consent Agreement by and among Tengion, Inc. and the investors party thereto, dated June 28, 2013

Exhibit 10.5 AMENDMENT, WAIVER AND CONSENT AGREEMENT This Amendment, Waiver and Consent Agreement (this “Agreement”) is entered into this 28th day of June, 2013, by and among Tengion, Inc., a Delaware corporation (the “Company”), and each party identified on the signature pages hereto (the “Investors”). RECITALS A. The Company and the Investors entered into that certain Securities Purchase Agreeme

July 5, 2013 EX-10.2

Facility Agreement by and among Tengion, Inc. and the lenders party thereto, dated June 28, 2013

Exhibit 10.2 FACILITY AGREEMENT FACILITY AGREEMENT (this “Agreement”), dated as of June 28, 2013, between Tengion, Inc., a Delaware corporation (the “Borrower”), and the lenders set forth on Schedule 1 attached hereto (the “Lenders” and, together with the Borrower, the “Parties”). W I T N E S S E T H: WHEREAS, the Borrower wishes to borrow from the Lenders $18,576,000.00 for the purpose described

July 5, 2013 8-K

Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant - TENGION, INC. FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 8-K Current Report Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 28, 2013 Tengion, Inc. (Exact name of registrant as specified in its charter) 001-34688 (Commission File Number) Delaware 20-0214813 (State or other jurisdiction of (I.R.S. Emplo

July 5, 2013 EX-99.1

Press Release, dated June 28, 2013

Exhibit 99.1 Investor and Media Contact: Brian Davis [email protected] 336.201.0155 Tengion Announces Transactions Totaling $33.6 Million to Advance its Organ Regeneration PlatformTM $15 Million Strategic Investment from Celgene Corporation and $18.6 Million Senior Secured Convertible Note Financing with New and Existing Investors WINSTON-SALEM, NC, July 1, 2013 - Tengion, Inc. (OTCQB: TNGN)

July 5, 2013 EX-4.3

Form of Warrants issued to Celgene Corporation on June 28, 2013

Exhibit 4.3 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAW, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS S

July 5, 2013 EX-10.7

Right of First Negotiation Agreement by and between Tengion, Inc. and Celgene Corporation, dated June 28, 2013

Exhibit 10.7 RIGHT OF FIRST NEGOTIATION AGREEMENT This Right of First Negotiation Agreement (this “Agreement”), dated June 28, 2013, is made by and among Tengion, Inc., a Delaware corporation, with a principal address at 3929 Westpoint Boulevard, Suite G, Winston-Salem, NC 27103 (“Tengion”) and Celgene Corporation, a Delaware corporation with a principal address at 86 Morris Avenue, Summit, New Je

July 5, 2013 EX-10.5

Amendment, Waiver and Consent Agreement by and among Tengion, Inc. and the investors party thereto, dated June 28, 2013

Exhibit 10.5 AMENDMENT, WAIVER AND CONSENT AGREEMENT This Amendment, Waiver and Consent Agreement (this “Agreement”) is entered into this 28th day of June, 2013, by and among Tengion, Inc., a Delaware corporation (the “Company”), and each party identified on the signature pages hereto (the “Investors”). RECITALS A. The Company and the Investors entered into that certain Securities Purchase Agreeme

July 5, 2013 EX-10.3

Security Agreement by and among Tengion, Inc. and the secured parties thereto, dated June 28, 2013

Exhibit 10.3 SECURITY AGREEMENT This Security Agreement (this “Agreement”), dated as of June 28, 2013, is entered into between TENGION, Inc. (“Obligor”) in favor of the parties identified as secured parties on the signature pages of this Agreement (together, the “Secured Party”). W I T N E S S E T H: WHEREAS, Obligor has entered into a Facility Agreement, dated as of the date hereof (the “Facility

July 5, 2013 EX-10.7

Right of First Negotiation Agreement by and between Tengion, Inc. and Celgene Corporation, dated June 28, 2013

Exhibit 10.7 RIGHT OF FIRST NEGOTIATION AGREEMENT This Right of First Negotiation Agreement (this “Agreement”), dated June 28, 2013, is made by and among Tengion, Inc., a Delaware corporation, with a principal address at 3929 Westpoint Boulevard, Suite G, Winston-Salem, NC 27103 (“Tengion”) and Celgene Corporation, a Delaware corporation with a principal address at 86 Morris Avenue, Summit, New Je

July 5, 2013 EX-10.5

Amendment, Waiver and Consent Agreement by and among Tengion, Inc. and the investors party thereto, dated June 28, 2013

Exhibit 10.5 AMENDMENT, WAIVER AND CONSENT AGREEMENT This Amendment, Waiver and Consent Agreement (this “Agreement”) is entered into this 28th day of June, 2013, by and among Tengion, Inc., a Delaware corporation (the “Company”), and each party identified on the signature pages hereto (the “Investors”). RECITALS A. The Company and the Investors entered into that certain Securities Purchase Agreeme

July 5, 2013 EX-4.2

Form of Warrants issued to various investors on June 28, 2013

Exhibit 4.2 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAW, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS S

July 5, 2013 EX-4.1

Form of Senior Secured Convertible Notes issued to various investors on June 28, 2013

Exhibit 4.1 THIS NOTE IS BEING ISSUED WITH ORIGINAL ISSUE DISCOUNT (“OID”), IN THE AMOUNT TO BE DETERMINED BY THE COMPANY AND WHICH WILL BE PROVIDED TO EACH HOLDER IN ACCORDANCE WITH APPLICABLE REGULATIONS. THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE SOLD, TRANSF

July 5, 2013 424B3

27,891,407 Shares Tengion, Inc.

Filed Pursuant to Rule 424(b)(3) Registration No. 333-186687 PROSPECTUS SUPPLEMENT NO. 8 (To Prospectus dated March 26, 2013) 27,891,407 Shares Tengion, Inc. This Prospectus Supplement No. 8 supplements the prospectus dated March 26, 2013 (as supplemented to date, the “Prospectus”), which forms a part of our Registration Statement on Form S-1 (Registration Statement No. 333-186687). The Prospectus

July 5, 2013 EX-10.4

Registration Rights Agreement by and among Tengion, Inc. and the parties thereto, dated June 28, 2013

Exhibit 10.4 REGISTRATION RIGHTS AGREEMENT REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 28, 2013 by and among Tengion, Inc., a Delaware corporation (the “Company”), those persons set forth on Schedule 1 to the Facility Agreement (as defined below) and Celgene Corporation (“Celgene”) (each individually, an “Investor” and together, the “Investors”). WHEREAS: A. In connection wi

July 5, 2013 EX-99.1

Tengion Announces Transactions Totaling $33.6 Million to Advance its Organ Regeneration PlatformTM $15 Million Strategic Investment from Celgene Corporation and $18.6 Million Senior Secured Convertible Note Financing with New and Existing Investors

Exhibit 99.1 Investor and Media Contact: Brian Davis [email protected] 336.201.0155 Tengion Announces Transactions Totaling $33.6 Million to Advance its Organ Regeneration PlatformTM $15 Million Strategic Investment from Celgene Corporation and $18.6 Million Senior Secured Convertible Note Financing with New and Existing Investors WINSTON-SALEM, NC, July 1, 2013 - Tengion, Inc. (OTCQB: TNGN)

July 5, 2013 EX-4.3

Form of Warrants issued to Celgene Corporation on June 28, 2013

Exhibit 4.3 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAW, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS S

July 5, 2013 EX-4.2

Form of Warrants issued to various investors on June 28, 2013

Exhibit 4.2 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAW, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS S

July 5, 2013 EX-10.2

Facility Agreement by and among Tengion, Inc. and the lenders party thereto, dated June 28, 2013

Exhibit 10.2 FACILITY AGREEMENT FACILITY AGREEMENT (this “Agreement”), dated as of June 28, 2013, between Tengion, Inc., a Delaware corporation (the “Borrower”), and the lenders set forth on Schedule 1 attached hereto (the “Lenders” and, together with the Borrower, the “Parties”). W I T N E S S E T H: WHEREAS, the Borrower wishes to borrow from the Lenders $18,576,000.00 for the purpose described

July 5, 2013 EX-99.1

Press Release, dated June 28, 2013

Exhibit 99.1 Investor and Media Contact: Brian Davis [email protected] 336.201.0155 Tengion Announces Transactions Totaling $33.6 Million to Advance its Organ Regeneration PlatformTM $15 Million Strategic Investment from Celgene Corporation and $18.6 Million Senior Secured Convertible Note Financing with New and Existing Investors WINSTON-SALEM, NC, July 1, 2013 - Tengion, Inc. (OTCQB: TNGN)

July 5, 2013 EX-10.6

Collaboration and Option Agreement by and among Tengion, Inc., Celgene Corporation and Celgene European Investment Company LLC, dated June 28, 2013

Exhibit 10.6 COLLABORATION AND OPTION AGREEMENT by and between TENGION, INC., CELGENE CORPORATION and CELGENE EUROPEAN INVESTMENT COMPANY LLC June 28, 2013 COLLABORATION AND OPTION AGREEMENT This Collaboration and Option Agreement (this “Agreement”) dated the 28th day of June, 2013 (the “Effective Date”) is by and among Tengion, Inc., a Delaware corporation having its principal office at 3929 West

July 5, 2013 EX-10.1

Securities Purchase Agreement by and among Tengion, Inc. and the investors party thereto, dated June 28, 2013

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of June 28, 2013 by and among Tengion, Inc. a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”). RECITALS A. The Company and the Purchasers are exec

July 5, 2013 EX-4.1

Form of Senior Secured Convertible Notes issued to various investors on June 28, 2013

Exhibit 4.1 THIS NOTE IS BEING ISSUED WITH ORIGINAL ISSUE DISCOUNT (“OID”), IN THE AMOUNT TO BE DETERMINED BY THE COMPANY AND WHICH WILL BE PROVIDED TO EACH HOLDER IN ACCORDANCE WITH APPLICABLE REGULATIONS. THE SECURITIES REPRESENTED BY THIS CERTIFICATE HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED, OR APPLICABLE STATE SECURITIES LAWS. THE SECURITIES MAY NOT BE SOLD, TRANSF

July 5, 2013 EX-10.7

Right of First Negotiation Agreement by and between Tengion, Inc. and Celgene Corporation, dated June 28, 2013

Exhibit 10.7 RIGHT OF FIRST NEGOTIATION AGREEMENT This Right of First Negotiation Agreement (this “Agreement”), dated June 28, 2013, is made by and among Tengion, Inc., a Delaware corporation, with a principal address at 3929 Westpoint Boulevard, Suite G, Winston-Salem, NC 27103 (“Tengion”) and Celgene Corporation, a Delaware corporation with a principal address at 86 Morris Avenue, Summit, New Je

July 5, 2013 EX-10.6

Collaboration and Option Agreement by and among Tengion, Inc., Celgene Corporation and Celgene European Investment Company LLC, dated June 28, 2013

Exhibit 10.6 COLLABORATION AND OPTION AGREEMENT by and between TENGION, INC., CELGENE CORPORATION and CELGENE EUROPEAN INVESTMENT COMPANY LLC June 28, 2013 COLLABORATION AND OPTION AGREEMENT This Collaboration and Option Agreement (this “Agreement”) dated the 28th day of June, 2013 (the “Effective Date”) is by and among Tengion, Inc., a Delaware corporation having its principal office at 3929 West

July 5, 2013 EX-10.4

Registration Rights Agreement by and among Tengion, Inc. and the parties thereto, dated June 28, 2013

Exhibit 10.4 REGISTRATION RIGHTS AGREEMENT REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 28, 2013 by and among Tengion, Inc., a Delaware corporation (the “Company”), those persons set forth on Schedule 1 to the Facility Agreement (as defined below) and Celgene Corporation (“Celgene”) (each individually, an “Investor” and together, the “Investors”). WHEREAS: A. In connection wi

July 5, 2013 EX-10.4

Registration Rights Agreement by and among Tengion, Inc. and the parties thereto, dated June 28, 2013

Exhibit 10.4 REGISTRATION RIGHTS AGREEMENT REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 28, 2013 by and among Tengion, Inc., a Delaware corporation (the “Company”), those persons set forth on Schedule 1 to the Facility Agreement (as defined below) and Celgene Corporation (“Celgene”) (each individually, an “Investor” and together, the “Investors”). WHEREAS: A. In connection wi

July 5, 2013 EX-10.3

Security Agreement by and among Tengion, Inc. and the secured parties thereto, dated June 28, 2013

Exhibit 10.3 SECURITY AGREEMENT This Security Agreement (this “Agreement”), dated as of June 28, 2013, is entered into between TENGION, Inc. (“Obligor”) in favor of the parties identified as secured parties on the signature pages of this Agreement (together, the “Secured Party”). W I T N E S S E T H: WHEREAS, Obligor has entered into a Facility Agreement, dated as of the date hereof (the “Facility

July 5, 2013 EX-10.2

Facility Agreement by and among Tengion, Inc. and the lenders party thereto, dated June 28, 2013

Exhibit 10.2 FACILITY AGREEMENT FACILITY AGREEMENT (this “Agreement”), dated as of June 28, 2013, between Tengion, Inc., a Delaware corporation (the “Borrower”), and the lenders set forth on Schedule 1 attached hereto (the “Lenders” and, together with the Borrower, the “Parties”). W I T N E S S E T H: WHEREAS, the Borrower wishes to borrow from the Lenders $18,576,000.00 for the purpose described

July 5, 2013 EX-10.1

Securities Purchase Agreement by and among Tengion, Inc. and the investors party thereto, dated June 28, 2013

Exhibit 10.1 SECURITIES PURCHASE AGREEMENT This Securities Purchase Agreement (this “Agreement”) is dated as of June 28, 2013 by and among Tengion, Inc. a Delaware corporation (the “Company”), and each purchaser identified on the signature pages hereto (each, including its successors and assigns, a “Purchaser” and collectively, the “Purchasers”). RECITALS A. The Company and the Purchasers are exec

July 5, 2013 EX-4.3

Form of Warrants issued to Celgene Corporation on June 28, 2013

Exhibit 4.3 THIS WARRANT AND THE SECURITIES ISSUABLE UPON EXERCISE HEREOF HAVE NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED (THE “SECURITIES ACT”), OR ANY STATE SECURITIES LAW, AND MAY NOT BE SOLD, TRANSFERRED, ASSIGNED, PLEDGED, HYPOTHECATED OR OTHERWISE DISPOSED OF OR EXERCISED UNLESS (I) A REGISTRATION STATEMENT UNDER THE SECURITIES ACT AND APPLICABLE STATE SECURITIES LAWS S

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