DBTX / Decibel Therapeutics Inc - Documents déposés auprès de la SEC, rapport annuel, procuration

Decibel Therapeutics Inc
US ˙ NASDAQ ˙ US24343R1068
CE SYMBOLE N'EST PLUS ACTIF

Statistiques de base
CIK 1656536
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Decibel Therapeutics Inc
SEC Filings (Chronological Order)
Cette page fournit une liste complète et chronologique des documents déposés auprès de la SEC, à l'exclusion des documents relatifs à la participation que nous fournissons ailleurs.
February 14, 2024 SC 13G/A

DBTX / Decibel Therapeutics Inc / CITADEL ADVISORS LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. 3)* DECIBEL THERAPEUTICS, INC. (Name of Issuer) Common Stock, $0.001 par value per share (the “Shares”) (Title of Class of Securities) 24343R10

October 10, 2023 15-12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Commission File Number: 001-40030 Decibel Therapeutics, Inc. (Exact name of registrant as specified

September 27, 2023 SC 13D/A

DBTX / Decibel Therapeutics Inc / Regeneron Pharmaceuticals Inc - SC 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Amendment No. 1) Under the Securities Exchange Act of 1934 Decibel Therapeutics, Inc. (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) 24343R106 (CUSIP Number) Joseph J. LaRosa Executive Vice President, General Counsel and Secretary Regeneron Pharmaceuticals, Inc. 777 Old Sa

September 25, 2023 SC 14D9/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 3) SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 3) SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Therapeutics, Inc. (Name of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 24343R 1

September 25, 2023 EX-2.2

CONTINGENT VALUE RIGHTS AGREEMENT

Exhibit 2.2 CONTINGENT VALUE RIGHTS AGREEMENT THIS CONTINGENT VALUE RIGHTS AGREEMENT, dated as of September 25, 2023 (this “Agreement”), is entered into by and among Regeneron Pharmaceuticals, Inc., a New York Corporation (“Parent”), Symphony Acquisition Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Purchaser”), and Computershare Inc., a Delaware corporation (“Compute

September 25, 2023 EX-3.1

AMENDED AND RESTATED CERTIFICATE OF INCORPORATION DECIBEL THERAPEUTICS, INC. ARTICLE I

Exhibit 3.1 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. ARTICLE I The name of the corporation is Decibel Therapeutics, Inc. (the “Corporation”). ARTICLE II The address, including street, number, city, and county, of the registered office of the Corporation in the State of Delaware is the Corporation Trust Company, 1209 Orange Street, City of Wilmington, County o

September 25, 2023 8-K

Changes in Control of Registrant, Material Modification to Rights of Security Holders, Completion of Acquisition or Disposition of Assets

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 25, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commissi

September 25, 2023 EX-3.2

AMENDED AND RESTATED DECIBEL THERAPEUTICS, INC. dated as of September 25, 2023

Exhibit 3.2 AMENDED AND RESTATED BY-LAWS of DECIBEL THERAPEUTICS, INC. dated as of September 25, 2023 TABLE OF CONTENTS ARTICLE I OFFICES SECTION 1. REGISTERED OFFICE 1 SECTION 2. OTHER OFFICES 1 ARTICLE II MEETINGS OF STOCKHOLDERS SECTION 1. ANNUAL MEETINGS 1 SECTION 2. SPECIAL MEETINGS 1 SECTION 3. VOTING 1 SECTION 4. QUORUM 2 SECTION 5. NOTICE OF MEETINGS 2 SECTION 6. ACTION WITHOUT MEETING 2 A

September 25, 2023 S-8 POS

As filed with the Securities and Exchange Commission on September 25, 2023

As filed with the Securities and Exchange Commission on September 25, 2023 Registration No.

September 25, 2023 S-8 POS

As filed with the Securities and Exchange Commission on September 25, 2023

As filed with the Securities and Exchange Commission on September 25, 2023 Registration No.

September 25, 2023 EX-99.25

EX-99.25

dbtx-form25

September 25, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 3) DECIBEL THERAPEUTICS, INC. (Name of Subject C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 3) DECIBEL THERAPEUTICS, INC. (Name of Subject Company) SYMPHONY ACQUISITION SUB, INC. (Offeror) REGENERON PHARMACEUTICALS, INC. (Parent of Offeror) (Names of Filing Persons) Common stock, par value

September 25, 2023 POS AM

As filed with the Securities and Exchange Commission on September 25, 2023

As filed with the Securities and Exchange Commission on September 25, 2023 Registration No.

September 25, 2023 EX-99.(A)(5)(A)

Regeneron Completes Acquisition of Decibel Therapeutics, Adding Promising Gene Therapy Programs for Hearing Loss

Exhibit (a)(5)(A) Press Release Regeneron Completes Acquisition of Decibel Therapeutics, Adding Promising Gene Therapy Programs for Hearing Loss TARRYTOWN, N.

September 25, 2023 S-8 POS

As filed with the Securities and Exchange Commission on September 25, 2023

As filed with the Securities and Exchange Commission on September 25, 2023 Registration No.

September 12, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 2) DECIBEL THERAPEUTICS, INC. (Name of Subject C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 2) DECIBEL THERAPEUTICS, INC. (Name of Subject Company) SYMPHONY ACQUISITION SUB, INC. (Offeror) REGENERON PHARMACEUTICALS, INC. (Parent of Offeror) (Names of Filing Persons) Common stock, par value

September 12, 2023 SC 14D9/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 2) SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 2) SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Therapeutics, Inc. (Name of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 24343R 1

September 8, 2023 SC 14D9/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 1) SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject C

SC 14D9/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Amendment No. 1) SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Therapeutics, Inc. (Name of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities

September 8, 2023 SC TO-T/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 1) DECIBEL THERAPEUTICS, INC. (Name of Subject C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 (Amendment No. 1) DECIBEL THERAPEUTICS, INC. (Name of Subject Company) SYMPHONY ACQUISITION SUB, INC. (Offeror) REGENERON PHARMACEUTICALS, INC. (Parent of Offeror) (Names of Filing Persons) Common stock, par value

August 25, 2023 EX-99.(A)(1)(B)

LETTER OF TRANSMITTAL To Tender Shares of Common Stock of DECIBEL THERAPEUTICS, INC. a Delaware corporation at $4.00 per share, payable in cash, plus one non-tradeable contractual contingent value right per share, which represents the contractual rig

 Exhibit (a)(1)(B) LETTER OF TRANSMITTAL To Tender Shares of Common Stock of DECIBEL THERAPEUTICS, INC.

August 25, 2023 SC TO-T

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 DECIBEL THERAPEUTICS, INC. (Name of Subject Company) SYMPHONY A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE TO Tender Offer Statement Pursuant to Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 DECIBEL THERAPEUTICS, INC. (Name of Subject Company) SYMPHONY ACQUISITION SUB, INC. (Offeror) REGENERON PHARMACEUTICALS, INC. (Parent of Offeror) (Names of Filing Persons) Common stock, par value $0.001 per share

August 25, 2023 EX-99.(D)(7)

Decibel Therapeutics, Inc. 1325 Boylston Street, Suite 500 Boston, MA 02215

Exhibit (d)(7) EXECUTION VERSION CONFIDENTIAL Decibel Therapeutics, Inc. 1325 Boylston Street, Suite 500 Boston, MA 02215 June 30, 2023 Regeneron Pharmaceuticals, Inc. 777 Old Saw Mill River Road Tarrytown, NY 10591-6707 Confidentiality Agreement In connection with your consideration of a possible negotiated business combination transaction involving Decibel Therapeutics, Inc. (together with its s

August 25, 2023 EX-99.(D)(8)

[Signature page follows]

Exhibit (d)(8) EXECUTION STRICTLY CONFIDENTIAL June 30, 2023 Decibel Therapeutics, Inc.

August 25, 2023 EX-99.(A)(1)(C)

Offer To Purchase All Outstanding Shares of Common Stock of DECIBEL THERAPEUTICS, INC. a Delaware corporation at $4.00 per share, payable in cash, plus one non-tradeable contingent value right (“CVR”) per share, which represents the contractual right

 Exhibit (a)(1)(C) Offer To Purchase All Outstanding Shares of Common Stock of DECIBEL THERAPEUTICS, INC.

August 25, 2023 EX-99.(A)(1)(A)

Offer to Purchase All Outstanding Shares of Common Stock of Decibel Therapeutics, Inc. at $4.00 per share, payable in cash, plus one non-tradeable contingent value right (“CVR”) per share , which represents the contractual right to receive contingent

TABLE OF CONTENTS  Exhibit (a)(1)(A) Offer to Purchase All Outstanding Shares of Common Stock of Decibel Therapeutics, Inc.

August 25, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 25, 2023 Decibel Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 25, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

August 25, 2023 EX-99.(A)(1)(E)

Notice of Offer to Purchase All Outstanding Shares of Common Stock DECIBEL THERAPEUTICS, INC. a Delaware corporation at $4.00 per share, payable in cash, plus one non-tradeable contingent value right (“CVR”) per share, which represents the contractua

Exhibit (a)(1)(E) This announcement is neither an offer to purchase nor a solicitation of an offer to sell Shares (as defined below), and the provisions herein are subject in their entirety to the provisions of the Offer (as defined below).

August 25, 2023 EX-99.(A)(1)(D)

Offer To Purchase All Outstanding Shares of Common Stock of DECIBEL THERAPEUTICS, INC. a Delaware corporation at $4.00 per share, payable in cash, plus one non-tradeable contingent value right (“CVR”) per share, which represents the contractual right

 Exhibit (a)(1)(D) Offer To Purchase All Outstanding Shares of Common Stock of DECIBEL THERAPEUTICS, INC.

August 25, 2023 EX-FILING FEES

Calculation of Filing Fee Tables Schedule TO-T (Rule 14d-100) DECIBEL THERAPEUTICS, INC. (Name of Subject Company (Issuer)) SYMPHONY ACQUISITION SUB, INC. a wholly owned subsidiary of REGENERON PHARMACEUTICALS, INC. (Names of Filing Persons (Offerors

Exhibit 107 Calculation of Filing Fee Tables Schedule TO-T (Rule 14d-100) DECIBEL THERAPEUTICS, INC.

August 25, 2023 SC 14D9

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Th

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Therapeutics, Inc. (Name of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 24343R 1

August 18, 2023 EX-99.4

JOINT FILING AGREEMENT

EX-99.4 3 tm2324112d1ex99-4.htm EXHIBIT 99.4 Exhibit 99.4 JOINT FILING AGREEMENT The undersigned hereby agree that they are filing this statement jointly pursuant to Rule 13d-1(k)(1). Each of them is responsible for the timely filing of such Schedule 13D and any amendments thereto, and for the completeness and accuracy of the information concerning such person contained therein; but none of them i

August 18, 2023 SC 13D

DBTX / Decibel Therapeutics Inc / Regeneron Pharmaceuticals Inc - SC 13D Activist Investment

SC 13D 1 tm2324112d1sc13d.htm SC 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 Decibel Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 24343R106 (CUSIP Number) Joseph J. LaRosa Executive Vice President, General Counsel and Secretary Regeneron Pharmaceutic

August 18, 2023 EX-99.3

DECIBEL THERAPEUTICS, INC. SERIES B PREFERRED STOCK PURCHASE AGREEMENT November 15, 2017

EX-99.3 2 tm2324112d1ex99-3.htm EXHIBIT 99.3 Exhibit 99.3 Execution Version DECIBEL THERAPEUTICS, INC. SERIES B PREFERRED STOCK PURCHASE AGREEMENT November 15, 2017 TABLE OF CONTENTS Page 1. Purchase and Sale of Preferred Stock 1 1.1 Sale and Issuance of Series B Preferred Stock 1 1.2 Closing; Delivery 1 1.3 Use of Proceeds 1 1.4 Defined Terms Used in this Agreement 1 2. Representations and Warran

August 11, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

August 11, 2023 EX-3.1

RESTATED CERTIFICATE OF INCORPORATION DECIBEL THERAPEUTICS, INC.

Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. Decibel Therapeutics, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware, does hereby certify that the name of the corporation is Decibel Therapeutics, Inc. and the original certificate of incorporation of the corporation was filed with the Secretary of State of the St

August 9, 2023 EX-2.1

Agreement and Plan of Merger, dated as of August 8, 2023, by and among Decibel Therapeutics, Inc., Regeneron Pharmaceuticals, Inc., and Symphony Acquisition Sub, Inc. (incorporated by reference to Exhibit 2.1 to the Form 8-K filed by Decibel Therapeutics, Inc. with the U.S. Securities and Exchange Commission on August 9, 2023).

EX-2.1 Exhibit 2.1 EXECUTION VERSION AGREEMENT AND PLAN OF MERGER among: Decibel Therapeutics, Inc., a Delaware corporation; Regeneron Pharmaceuticals, Inc., a New York corporation; and Symphony Acquisition Sub, Inc., a Delaware corporation Dated as of August 8, 2023 Table of Contents Section 1 THE OFFER 1.1 The Offer 5 1.2 Company Actions 9 Section 2 MERGER TRANSACTION 2.1 Merger of Purchaser int

August 9, 2023 EX-99.1

Regeneron to Acquire Decibel Therapeutics, Strengthening Gene Therapy and Hearing Loss Programs

Exhibit 99.1 Press Release Regeneron to Acquire Decibel Therapeutics, Strengthening Gene Therapy and Hearing Loss Programs Proposed acquisition builds on existing collaboration between Decibel and Regeneron, will accelerate and further resource key gene therapy programs for hearing loss Decibel’s lead investigational gene therapy DB-OTO, designed to provide hearing to people with otoferlin-related

August 9, 2023 EX-2.2

Form of Contingent Value Rights Agreement, by and among Regeneron Pharmaceuticals, Inc., Symphony Acquisition Sub, Inc., and a rights agent mutually agreeable to Regeneron Pharmaceuticals, Inc. and Decibel Therapeutics, Inc. (incorporated by reference to Exhibit 2.2 to the Form 8-K filed by Decibel Therapeutics, Inc. with the U.S. Securities and Exchange Commission on August 9, 2023).

EX-2.2 Exhibit 2.2 FORM OF CONTINGENT VALUE RIGHTS AGREEMENT THIS CONTINGENT VALUE RIGHTS AGREEMENT, dated as of [•] (this “Agreement”), is entered into by and among Regeneron Pharmaceuticals, Inc., a New York Corporation (“Parent”), Symphony Acquisition Sub, Inc., a Delaware corporation and a wholly owned subsidiary of Parent (“Purchaser”), and [•], a [•], as Rights Agent. PREAMBLE WHEREAS, Decib

August 9, 2023 EX-99.3

Email to Partners

Exhibit 99.3 Email to Partners Subject: Exciting update from Decibel Therapeutics Dear [INSERT NAME], Today Decibel Therapeutics and Regeneron Pharmaceuticals announced an agreement for Decibel to be acquired by Regeneron, a leading biotechnology company. This enables Decibel to build on our existing, long-standing collaboration with Regeneron to direct extensive support and resources to advance o

August 9, 2023 EX-99.7

Announcements by the Company and the Company’s management via X on August 9, 2023

Exhibit 99.7 Announcements by the Company and the Company’s management via X on August 9, 2023 On August 9, 2023, Decibel Therapeutics, Inc. (the “Company”) made the following announcements via X regarding the proposed acquisition of the Company by Regeneron Pharmaceuticals, Inc., a New York corporation (“Parent”), and proposed merger of the Company with Symphony Acquisition Sub, Inc., a Delaware

August 9, 2023 SC14D9C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Th

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 SOLICITATION/RECOMMENDATION STATEMENT UNDER SECTION 14(d)(4) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Decibel Therapeutics, Inc. (Name of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 24343R 106 (CUSIP Number o

August 9, 2023 EX-99.6

Announcements by the Company and the Company’s management via LinkedIn on August 9, 2023

Exhibit 99.6 Announcements by the Company and the Company’s management via LinkedIn on August 9, 2023 On August 9, 2023, Decibel Therapeutics, Inc. (the “Company”) made the following announcements via LinkedIn regarding the proposed acquisition of the Company by Regeneron Pharmaceuticals, Inc., a New York corporation (“Parent”), and proposed merger of the Company with Symphony Acquisition Sub, Inc

August 9, 2023 EX-99.1

TENDER AND SUPPORT AGREEMENT

EX-99.1 Exhibit 99.1 TENDER AND SUPPORT AGREEMENT This TENDER AND SUPPORT AGREEMENT (this “Agreement”), dated as of August 8, 2023, is entered into by and among Regeneron Pharmaceuticals, Inc., a New York corporation (“Parent”), Symphony Acquisition Sub, Inc., a Delaware corporation and wholly owned subsidiary of Parent (“Purchaser”), and each of the persons set forth on Schedule A hereto (each, a

August 9, 2023 EX-99.2

Email from Laurence Reid to Decibel Therapeutics Employees

Exhibit 99.2 Email from Laurence Reid to Decibel Therapeutics Employees Subject: Important Company News Dear Colleagues, I am pleased to share with you that today we announced an agreement for Decibel Therapeutics to be acquired by Regeneron Pharmaceuticals, a long-standing collaborator and leading biotechnology company. The press release with full details of this news can be found here [INSERT LI

August 9, 2023 EX-99.2

-2-

Exhibit 99.2 Twitter Post LinkedIn Post Instagram Stories Post -2- Forward-Looking Statements This communication contains forward-looking statements that involve risks and uncertainties relating to future events and the future performance of Regeneron Pharmaceuticals, Inc. (“Regeneron”) and Decibel Therapeutics, Inc. (“Decibel”), including regarding Regeneron’s proposed acquisition of Decibel, the

August 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 8, 2023 Decibel Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 8, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission F

August 9, 2023 EX-99.2

1/6

EX-99.2 Exhibit 99.2 Press Release Regeneron to Acquire Decibel Therapeutics, Strengthening Gene Therapy and Hearing Loss Programs Proposed acquisition builds on existing collaboration between Decibel and Regeneron, will accelerate and further resource key gene therapy programs for hearing loss Decibel’s lead investigational gene therapy DB-OTO, designed to provide hearing to people with otoferlin

August 9, 2023 EX-99.4

Email to Advocacy Groups

Exhibit 99.4 Email to Advocacy Groups Subject: Exciting update from Decibel Therapeutics Hi [INSERT NAME], I am writing to share an exciting update from Decibel Therapeutics. Today Decibel and Regeneron Pharmaceuticals announced an agreement for Decibel to be acquired by Regeneron, one of our long-standing collaborators and a leading biotechnology company. The press release with full details of th

August 9, 2023 EX-99.5

Email to Clinical Trial Investigators

Exhibit 99.5 Email to Clinical Trial Investigators Subject: Exciting update from Decibel Therapeutics Hi [INSERT NAME] Today Decibel Therapeutics and Regeneron Pharmaceuticals announced an agreement for Decibel to be acquired by Regeneron, our longtime collaborator and co-developer of our DB-OTO gene therapy product candidate. The press release with full details of this news can be found here [INS

August 9, 2023 SC TO-C

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO (RULE 14d-100) Tender Offer Statement under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Decibel Therapeutics, Inc. (Name of Subject Company) S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE TO (RULE 14d-100) Tender Offer Statement under Section 14(d)(1) or 13(e)(1) of the Securities Exchange Act of 1934 Decibel Therapeutics, Inc. (Name of Subject Company) Symphony Acquisition Sub, Inc. (Offeror) Regeneron Pharmaceuticals, Inc. (Parent of Offeror) (Names of Filing Persons) COMMON STOCK, $0.001 PAR VALUE P

June 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 13, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commissio

May 15, 2023 EX-10.3

Second Amendment, dated as of March 13, 2023, to the License Agreement, by and between the University of Florida Research Foundation, Inc. and the Registrant.

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential.

May 15, 2023 EX-10.2

Amended and Restated Exclusive License Agreement, dated as of March 10, 2023, by and between the Curators of the University of Missouri and the Registrant.

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential.

May 15, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

April 28, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

DEF 14A 1 dbtxdef14a2023proxyv.htm DEF 14A Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of t

April 28, 2023 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ☐ Defin

April 14, 2023 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule 14

April 6, 2023 EX-3

Amended and Restated Bylaws of Decibel Therapeutics, Inc.

Exhibit 3.1 AMENDED AND RESTATED BYLAWS OF DECIBEL THERAPEUTICS, INC. TABLE OF CONTENTS Page ARTICLE I STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Record Date for Stockholder Meetings 1 1.5 Notice of Meetings 1 1.6 Voting List 1 1.7 Quorum 2 1.8 Adjournments 2 1.9 Voting and Proxies 2 1.10 Action at Meeting 2 1.11 Nomination of Directors 3 1.12 Notice of

April 6, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 4, 2023 Decibel Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 4, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 21, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 19, 2023 Decibel Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 19, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission F

March 14, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Decibel Therapeutics, Inc.

March 14, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-40030 DECIBEL THERAP

March 14, 2023 S-8

As filed with the Securities and Exchange Commission on March 14, 2023

As filed with the Securities and Exchange Commission on March 14, 2023 Registration No.

March 14, 2023 EX-10

Second Amendment, dated February 6, 2023, to the License and Collaboration Agreement, dated as of November 15, 2017, as amended, by and between Regeneron Pharmaceuticals, Inc. and Decibel Therapeutics, Inc. (incorporated by reference to Exhibit 10.30 to the Annual Report on Form 10-K, File No. 001-40030, filed by Decibel Therapeutics, Inc. on March 14, 2023).

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential.

March 13, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 10, 2023 Decibel Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 10, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission F

February 14, 2023 SC 13G/A

DBTX / Decibel Therapeutics Inc / CITADEL ADVISORS LLC - SC 13G/A Passive Investment

SC 13G/A 1 tm233236-8sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2 (Amendment No. 2)* Decibel Therapeutics, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (the “Shares”

January 9, 2023 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 9, 2023 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

January 9, 2023 EX-99.1

This presentation contains forward looking statements that involve substantial risks and uncertainties. All statements, other than statements of historical facts, contained in this presentation, including statements regarding Decibel Therapeutics, In

A WORLD OF CONNECTION FOR PEOPLE WITH HEARING AND BALANCE DISORDERSTM 41st Annual Healthcare Meeting January 2023 Exhibit 99.

November 9, 2022 EX-10.1

Letter Agreement, dated September 9, 2022, by and between the Registrant and Elisabeth Leiderman.

Exhibit 10.1 VIA ELECTRONIC MAIL September 9, 2022 Elisabeth Leiderman [Address] [Address] [Address] Dear Lis: As we have discussed, your employment with Decibel Therapeutics, Inc. (the ?Company?) will end effective October 7, 2022 (the ?Separation Date?). As we also discussed, if you (a) sign and return this letter agreement to me by September 16, 2022; (b) sign the Additional Release attached he

November 9, 2022 EX-10.2

Amended and Restated 2021 Employee Stock Purchase Plan.

Exhibit 10.2 Decibel Therapeutics, Inc. 2021 EMPLOYEE STOCK PURCHASE PLAN The purpose of this Amended and Restated 2021 Employee Stock Purchase Plan (this ?Plan?) is to provide eligible employees of Decibel Therapeutics, Inc. (the ?Company?) and certain of its subsidiaries with opportunities to purchase shares of the Company?s common stock, $0.001 par value per share (the ?Common Stock?), commenci

November 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

October 17, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 17, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

October 12, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 10, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

September 20, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 20, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commissi

September 13, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 9, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commissio

August 10, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 10, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

August 10, 2022 EX-10.2

First Amendment, dated as of June 13, 2022, to the License Agreement, dated as of October 29, 2020, by and between the University of Florida Research Foundation, Incorporated and the Registrant.

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential.

August 10, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

August 10, 2022 424B5

Decibel Therapeutics, Inc. Up to $50,000,000 Common Stock

Table of Contents Filed pursuant to Rule 424(b)(5) Registration Statement No. 333-263671 PROSPECTUS SUPPLEMENT (to Prospectus dated May 17, 2022) Decibel Therapeutics, Inc. Up to $50,000,000 Common Stock We have entered into an Open Market Sale AgreementSM, dated as of March 18, 2022, or the sales agreement, with Jefferies LLC, or Jefferies, relating to the sale of shares of our common stock, par

August 10, 2022 EX-10.1

Second Amendment, dated as of May 3, 2022, to the License Agreement, dated as of August 26, 2019, by and between the Curators of the University of Missouri and the Registrant.

Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) is the type of information that the registrant treats as private or confidential.

June 28, 2022 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 28, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission Fi

June 17, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 17, 2022 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Its Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commissio

May 13, 2022 CORRESP

Decibel Therapeutics, Inc. 1325 Boylston Street, Suite 500 Boston, Massachusetts 02215 May 13, 2022

Decibel Therapeutics, Inc. 1325 Boylston Street, Suite 500 Boston, Massachusetts 02215 May 13, 2022 VIA EDGAR SUBMISSION U.S. Securities and Exchange Commission Division of Corporation Finance, Office of Life Sciences 100 F Street, N.E. Washington, D.C. 20549 Attention: Christine Westbrook Re: Decibel Therapeutics, Inc. Registration Statement on Form S-3 Filed March 18, 2022 File No. 333-263671 Re

May 12, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

April 29, 2022 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2)) ? Defin

April 29, 2022 DEF 14A

definitive proxy statement

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant ? Filed by a Party other than the Registrant ? Check the appropriate box: ? Preliminary Proxy Statement ? Confidential, for Use of the Commission Only (as permitted by Rule 14

March 18, 2022 EX-4.3

Form of Senior Indenture

Exhibit 4.3 DECIBEL THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SENIOR DEBT SECURITIES CROSS-REFERENCE TABLE1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 314(b) In

March 18, 2022 S-8

As filed with the Securities and Exchange Commission on March 18, 2022

As filed with the Securities and Exchange Commission on March 18, 2022 Registration No.

March 18, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-8 (Form Type) Decibel Therapeutics, Inc.

March 18, 2022 EX-4.6

Form of Subordinated Note

Exhibit 4.6 Form of Subordinated Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE

March 18, 2022 S-3

As filed with the Securities and Exchange Commission on March 18, 2022

Table of Contents As filed with the Securities and Exchange Commission on March 18, 2022 Registration No.

March 18, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-40030 DECIBEL THERAP

March 18, 2022 EX-1.2

Open Market Sale AgreementSM, dated as of March 18, 2022, by and between the Company and Jefferies LLC (incorporated by reference to Exhibit 1.2 to the Company’s Registration Statement on Form S-3, File No. 333-263671, filed March 18, 2022).

Exhibit 1.2 OPEN MARKET SALE AGREEMENT March 18, 2022 JEFFERIES LLC 520 Madison Avenue New York, New York 10022 Ladies and Gentlemen: Decibel Therapeutics, Inc., a Delaware corporation (the ?Company?), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sales agent and/or principal (the ?Agent?), shares of the Company?s common

March 18, 2022 EX-4.4

Form of Subordinated Indenture

Exhibit 4.4 DECIBEL THERAPEUTICS, INC. and Trustee INDENTURE Dated as of SUBORDINATED DEBT SECURITIES CROSS-REFERENCE TABLE 1 Section of Trust Indenture Act of 1939, as amended Section of Indenture 310(a) 6.09 310(b) 6.08 6.10 310(c) Inapplicable 311(a) 6.13 311(b) 6.13 311(c) Inapplicable 312(a) 4.01 4.04 312(b) 4.04(c) 312(c) 4.04(c) 313(a) 4.03 313(b) 4.03 313(c) 4.03 313(d) 4.03 314(a) 4.02 31

March 18, 2022 EX-4.5

Form of Senior Note

Exhibit 4.5 Form of Senior Note (FACE OF SECURITY) [Each Global Security shall bear substantially the following legend: UNLESS AND UNTIL IT IS EXCHANGED IN WHOLE OR IN PART FOR SECURITIES IN DEFINITIVE REGISTERED FORM, THIS SECURITY MAY NOT BE TRANSFERRED EXCEPT AS A WHOLE BY THE DEPOSITARY TO A NOMINEE OF THE DEPOSITARY OR BY A NOMINEE OF THE DEPOSITARY TO THE DEPOSITARY OR ANOTHER NOMINEE OF THE

March 18, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Decibel Therapeutics, Inc.

February 14, 2022 EX-99.1

Joint Filing Agreement

EXHIBIT 99.1 Joint Filing Agreement The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing statements. The undersigned acknowledge that each shall be

February 14, 2022 EX-99.24

POWER OF ATTORNEY

EXHIBIT 24 POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, that the undersigned hereby constitutes and appoints Kevin Gillis his true and lawful attorney-in-fact, with full power of substitution, to sign any and all instruments, certificates and documents that may be necessary, desirable or appropriate to be executed on behalf of himself as an individual or in his capacity as a direct or indirec

February 14, 2022 SC 13G/A

DBTX / Decibel Therapeutics Inc / CITADEL ADVISORS LLC - DECIBEL THERAPEUTICS, INC. Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO ? 240.13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO ? 240.13d-2 (Amendment No. 1)* Decibel Therapeutics Inc (Name of Issuer) Common Stock, $0.001 par value per share (the ?Shares?) (Title of Class of Securities) 24343R106

February 14, 2022 SC 13G

DBTX / Decibel Therapeutics Inc / GV 2016, L.P. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Decibel Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 24343R106 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate t

February 14, 2022 SC 13G

DBTX / Decibel Therapeutics Inc / Third Rock Ventures III, L.P. - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* Decibel Therapeutics, Inc. (Name of Issuer) COMMON STOCK, $0.001 PAR VALUE PER SHARE (Title of Class of Securities) 24343R106 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate t

February 14, 2022 EX-99.A

Agreement of Joint Filing

EXHIBIT A Agreement of Joint Filing The undersigned hereby agree that a single Schedule 13G (or any amendment thereto) relating to the Common Stock of Decibel Therapeutics, Inc.

February 11, 2022 SC 13G

DBTX / Decibel Therapeutics Inc / Regeneron Pharmaceuticals Inc - SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Decibel Therapeutics, Inc. (Name of Issuer) Common Stock, par value $0.001 per share (Title of Class of Securities) 24343R106 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate t

December 7, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 3, 2021 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

November 10, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

August 17, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 13, 2021 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission

August 10, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

August 10, 2021 EX-10.1

Form of Severance and Change in Control Benefits Agreement

Exhibit 10.1 Form of Severance and Change in Control Benefits Agreement This Severance and Change in Control Benefits Agreement ((the ?Agreement?) is entered into between Decibel Therapeutics, Inc. (the ?Company,? which term shall include any successor by merger, consolidation, sale of substantially all of the Company?s assets or otherwise) and (?you?) (collectively, the ?Parties?), effective as o

June 3, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 2, 2021 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission Fil

May 13, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-40030 Decibel Therapeutics, Inc.

April 13, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 7, 2021 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission Fi

March 29, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-40030 DECIBEL THERAP

March 29, 2021 EX-99.1

Decibel Therapeutics Reports Fourth Quarter and Full Year 2020 and Financial Results and Corporate Update -Successfully completed an oversubscribed Series D financing and upsized Initial Public Offering raising approximately $220.1M in gross proceeds

Exhibit 99.1 Decibel Therapeutics Reports Fourth Quarter and Full Year 2020 and Financial Results and Corporate Update -Successfully completed an oversubscribed Series D financing and upsized Initial Public Offering raising approximately $220.1M in gross proceeds- -Established development and manufacturing agreement for otoferlin dual-vector gene therapy with Catalent- -Launched AmplifyTM genetic

March 29, 2021 EX-4.3

Description of Securities Registered Under Section 12 of the Exchange Act

Exhibit 4.3 DESCRIPTION OF SECURITIES REGISTERED UNDER SECTION 12 OF THE SECURITIES EXCHANGE ACT OF 1934 The following description of the common stock, par value $0.001 per share, of Decibel Therapeutics, Inc. (?us,? ?our,? ?we? or the ?Company?), which is the only security of the Company registered under Section 12 of the Securities Exchange Act of 1934, as amended (the ?Exchange Act?), summarize

March 29, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 29, 2021 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commission F

March 2, 2021 EX-99.1

JOINT FILING AGREEMENT

Exhibit 1 JOINT FILING AGREEMENT The undersigned hereby agree that the Statement on Schedule 13D, dated March 1, 2021, with respect to the common stock of Decibel Therapeutics, Inc.

March 2, 2021 SC 13D

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 Decibel Therapeutics, Inc. (Name of Issuer) Common Stock (Title of Class of Securities) 24343R106 (CUSIP Number) OrbiMed Advisors LLC OrbiMed Capital GP VIII LLC OrbiMed Genesis GP LLC OrbiMed Capital LLC 601 Lexington Avenue, 54th Floor New York, NY 10022 Telephone: (212)

March 1, 2021 SC 13G

NUMBER OF OWNED BY

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G*/ (Rule 13d-102) Decibel Therapeutics, Inc. (Name of Issuer) Common stock, par value $0.001 per share (Title of Class of Securities) 24343R106 (CUSIP Number) February 17, 2021 Date of Event Which Requires Filing of the Statement Check the appropriate box to designate the rule pursuant to which this Schedule is fil

February 19, 2021 S-8

- S-8

As filed with the Securities and Exchange Commission on February 19, 2021 Registration No.

February 17, 2021 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 17, 2021 Decibel Therapeutics, Inc. (Exact Name of Registrant as Specified in Charter) Delaware 001-40030 46-4198709 (State or Other Jurisdiction of Incorporation) (Commissio

February 17, 2021 EX-3.1

Restated Certificate of Incorporation of the Registrant (incorporated by reference to Exhibit 3.1 to the Registrant’s Current Report on Form 8-K (File No. 001-40030) filed with the Securities and Exchange Commission on February 17, 2021).

Exhibit 3.1 RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. Decibel Therapeutics, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware, does hereby certify that the name of the corporation is Decibel Therapeutics, Inc. and the original certificate of incorporation of the corporation was filed with the Secretary of State of the St

February 17, 2021 EX-3.2

Amended and Restated Bylaws of the Registrant (incorporated by reference to Exhibit 3.2 to the Registrant’s Current Report on Form 8-K (File No. 001-40030) filed with the Securities and Exchange Commission on February 17, 2021).

Exhibit 3.2 AMENDED AND RESTATED BYLAWS OF DECIBEL THERAPEUTICS, INC. TABLE OF CONTENTS Page ARTICLE I STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Record Date for Stockholder Meetings 1 1.5 Notice of Meetings 2 1.6 Voting List 2 1.7 Quorum 3 1.8 Adjournments 3 1.9 Voting and Proxies 4 1.10 Action at Meeting 4 1.11 Nomination of Directors 5 1.12 Notice of

February 12, 2021 424B4

7,062,000 Shares Common Stock

Table of Contents Filed Pursuant to Rule 424(b)(4) File No. 333-252347 File No. 333-253012 PROSPECTUS 7,062,000 Shares Common Stock This is an initial public offering of common stock by Decibel Therapeutics, Inc. We are selling 7,062,000 shares of our common stock. The initial public offering price is $18.00 per share. We have granted the underwriters an option for a period of 30 days from the dat

February 11, 2021 S-1MEF

- S-1MEF

S-1MEF As filed with the Securities and Exchange Commission on February 11, 2021 Registration No.

February 9, 2021 CORRESP

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Decibel Therapeutics, Inc. 1325 Boylston St., Suite 500 Boston, MA 02215 February 9, 2021 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attention: Jason Drory Re: Decibel Therapeutics, Inc. Registration Statement on Form S-1 File No. 333-252347 Request for Acceleration Ladies and Gentlemen: Pursuant to Rule 461 promulgat

February 9, 2021 CORRESP

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February 9, 2021 VIA EDGAR U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Attn: Jason Drory Re: Decibel Therapeutics, Inc. (the ?Company?) Registration Statement on Form S-1 File No. 333-252347 Acceleration Request Requested Date: February 11, 2021 Requested Time: 4:00 p.m., Eastern Standard Time Ladies and Gentlemen: In accordance

February 8, 2021 EX-3.5

Certificate of Amendment to the Fourth Amended and Restated Certificate of Incorporation of the Registrant, effective as of February 5, 2021

EX-3.5 Exhibit 3.5 CERTIFICATE OF AMENDMENT TO THE FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. Decibel Therapeutics, Inc. (the “Corporation”), a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “General Corporation Law”), does hereby certify as follows: A resolution was duly adopted by the

February 8, 2021 EX-10.2

2015 Stock Incentive Plan, as amended

EX-10.2 Exhibit 10.2 2015 STOCK INCENTIVE PLAN OF DECIBEL THERAPEUTICS, INC. i TABLE OF CONTENTS Page 1. Purpose 1 2. Eligibility 1 3. Administration and Delegation 1 (a) Administration by the Board 1 (b) Appointment of Committees 1 4. Stock Available for Awards 2 (a) Number of Shares 2 (b) Substitute Awards 2 5. Stock Options 2 (a) General 2 (b) Incentive Stock Options 2 (c) Exercise Price 3 (d)

February 8, 2021 EX-1.1

Form of Underwriting Agreement

EX-1.1 Exhibit 1.1 Decibel Therapeutics, Inc. [] Shares Common Stock ($0.001 par value per share) Underwriting Agreement New York, New York [ ], 2021 Citigroup Global Markets Inc. SVB Leerink LLC As Representatives of the several Underwriters, c/o Citigroup Global Markets Inc. 388 Greenwich Street New York, New York 10013 c/o SVB Leerink LLC One Federal Street, 37th Floor Boston, MA 02110 Ladies a

February 8, 2021 S-1/A

- S-1/A

S-1/A Table of Contents As filed with the Securities and Exchange Commission on February 8, 2021 Registration No.

February 8, 2021 8-A12B

Form 8-A

8-A12B UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-A FOR REGISTRATION OF CERTAIN CLASSES OF SECURITIES PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 Decibel Therapeutics, Inc. (Exact name of registrant as specified in its charter) Delaware 46-4198709 (State of incorporation or organization) (I.R.S. Employer Identification No.) 1325 Boyls

February 8, 2021 EX-10.10

2021 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.10 to the Registrant’s Registration Statement on Form S-1 (File No. 333-252347) filed with the Securities and Exchange Commission on February 8, 2021.

EX-10.10 Exhibit 10.10 Decibel Therapeutics, Inc. 2021 EMPLOYEE STOCK PURCHASE PLAN The purpose of this 2021 Employee Stock Purchase Plan (this “Plan”) is to provide eligible employees of Decibel Therapeutics, Inc. (the “Company”) and certain of its subsidiaries with opportunities to purchase shares of the Company’s common stock, $0.001 par value per share (the “Common Stock”), commencing at such

February 8, 2021 EX-10.6

2021 Stock Incentive Plan (incorporated by reference to Exhibit 10.6 to the Registrant’s Registration Statement on Form S-1 (File No. 333-252347) filed with the Securities and Exchange Commission on February 8, 2021.

EX-10.6 Exhibit 10.6 Decibel Therapeutics, Inc. 2021 STOCK INCENTIVE PLAN 1. Purpose The purpose of this 2021 Stock Incentive Plan (the “Plan”) of Decibel Therapeutics, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to

February 3, 2021 EX-10.27

First Amendment, dated as of February 3, 2021, to the License Agreement, dated as of August 26, 2019, by and between the Curators of the University of Missouri and the Registrant (incorporated by reference to Exhibit 10.27 to the Registrant’s Registration Statement on Form S-1/A, File No. 333-252347, filed February 3, 2021).

EX-10.27 Exhibit 10.27 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. FIRST AMENDMENT TO THE LICENSE AGREEMENT DATED 8/26/2019 BETWEEN THE CURATORS OF THE UNIVERSITY OF MISSOURI AND DECIBEL THERAPEUTICS, INC. This FIRST AMENDM

February 3, 2021 S-1/A

- S-1/A

S-1/A As filed with the Securities and Exchange Commission on February 3, 2021 Registration No.

January 28, 2021 EX-4.1

Specimen Stock Certificate Evidencing Shares of Common Stock (incorporated by reference to Exhibit 4.1 to the Registrant’s Registration Statement on Form S-1/A, File No. 333-252347, filed January 28, 2021).

EX-4.1 Exhibit 4.1 COMMON STOCK COMMON STOCK PAR VALUE $0.001 Certificate Number ZQ00000000 Shares **000000****************** ***000000***************** ****000000**************** *****000000*************** ******000000************** Decibel THERAPEUTICS DECIBEL THERAPEUTICS, INC. INCORPORATED UNDER THE LAWS OF THE STATE OF DELAWARE THIS CERTIFIES THAT MR. SAMPLE & MRS. SAMPLE & MR. SAMPLE & MRS.

January 28, 2021 S-1/A

- S-1/A

S-1/A Table of Contents As filed with the Securities and Exchange Commission on January 28, 2021 Registration No.

January 28, 2021 CORRESP

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January 28, 2021 By Electronic Submission U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, DC 20549 Stuart M. Falber +1 617 526 6663 (t) +1 617 526 5000 (f) wilmerhale.com [email protected] Attention: Jason Drory Re: Decibel Therapeutics, Inc. Amendment No. 1 to Draft Registration Statement on Form S-1 Submitted January 12, 2021 CIK

January 27, 2021 CORRESP

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CORRESP 1 filename1.htm +1 617 526 6000 (t) +1 617 526 5000 (f) FOIA CONFIDENTIAL TREATMENT REQUEST UNDER RULE 83 The entity requesting confidential treatment is: Decibel Therapeutics, Inc. 1325 Boylston Street, Suite 500 Boston, Massachusetts 02215 Attn: Laurence Reid, Ph.D. President and Chief Executive Officer (617) 370-8701 January 27, 2021 VIA EDGAR SUBMISSION AND SECURE FILE TRANSFER U.S. Se

January 22, 2021 EX-10.7

Form of Stock Option Agreement under the 2021 Stock Incentive Plan

EX-10.7 Exhibit 10.7 Decibel Therapeutics, Inc. STOCK OPTION AGREEMENT Decibel Therapeutics, Inc. (the “Company”) hereby grants the following stock option pursuant to its 2021 Stock Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of optionee (the “Participant”): Grant Date: Incentive Stock Option or Nonstatutory Stock Option: Number of shares o

January 22, 2021 EX-4.2

Third Amended and Restated Investors’ Rights Agreement, dated as of November 2, 2020, by and among the Registrant and the other parties thereto

EX-4.2 Exhibit 4.2 Execution Version DECIBEL THERAPEUTICS, INC. THIRD AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT November 2, 2020 TABLE OF CONTENTS Page 1. Definitions. 1 2. Registration Rights. 5 2.1 Demand Registration. 5 2.2 Company Registration. 6 2.3 Underwriting Requirements. 7 2.4 Obligations of the Company. 8 2.5 Furnish Information. 9 2.6 Expenses of Registration. 10 2.7 Delay of Re

January 22, 2021 EX-21.1

Subsidiaries of the Registrant

EX-21.1 Exhibit 21.1 SUBSIDIARIES OF THE REGISTRANT Name of subsidiary Jurisdiction of incorporation or organization Decibel Securities Corporation Massachusetts Decibel Therapeutics Australia Pty Ltd Australia

January 22, 2021 EX-10.24

Form of Change in Control Agreement

EX-10.24 Exhibit 10.24 Name Address Re: Decibel Therapeutics, Inc. Change in Control Agreement Dear: The Company desires to provide you with accelerated vesting of equity in the event of termination after a change in control (as defined herein) in certain circumstances. Accordingly, the Company agrees to provide a change in control benefit to you on the terms and conditions set forth in this Chang

January 22, 2021 EX-10.17

Offer of Employment, dated as of October 28, 2020, by and between the Registrant and Laurence Reid, Ph.D.

EX-10.17 Exhibit 10.17 October 28, 2020 Laurence Reid Re: Offer of Employment Dear Laurence: Decibel Therapeutics, Inc. (the “Company”) is pleased to confirm its offer to employ you as Chief Executive Officer. 1. Date of Hire. Your effective date of hire as an employee (the “Start Date”) shall be Monday, November 2, 2020 unless another date is agreed upon by you and the Company. 2. Compensation. Y

January 22, 2021 EX-10.22

Offer of Employment, dated as of December 19, 2017, by and between the Registrant and Anna Trask

EX-10.22 Exhibit 10.22 December 19, 2017 Re: Offer of Employment Dear Anna: Decibel Therapeutics, Inc. (the “company”) is pleased to confirm its offer to employ you as Vice President, People, Community. and Culture reporting to Steve Holtzman. Chief Executive Officer. Your effective date of hire as an employee (the “Start Date”) shall be no later than January 2, 2018 unless another date is agreed

January 22, 2021 EX-3.3

Form of Restated Certificate of Incorporation of the Registrant (to be effective upon the closing of this offering)

EX-3.3 Exhibit 3.3 RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. Decibel Therapeutics, Inc., a corporation organized and existing under the General Corporation Law of the State of Delaware, does hereby certify that the name of the corporation is Decibel Therapeutics, Inc. and the original certificate of incorporation of the corporation was filed with the Secretary of State of

January 22, 2021 EX-3.2

Bylaws of the Registrant

EX-3.2 Exhibit 3.2 BY-LAWS OF HEARING, INC. (the “Corporation”) 1. Stockholders (a) Annual Meeting. The annual meeting of stockholders shall be held for the election of directors each year at such place, date and time as shall be designated by the Board of Directors. Any other proper business may be transacted at the annual meeting. If no date for the annual meeting is established or said meeting

January 22, 2021 EX-10.3

Form of Restricted Stock Agreement under the 2015 Stock Incentive Plan

EX-10.3 Exhibit 10.3 [NOTE: UNLESS THE SHARES ARE FULLY VESTED UPON GRANT, IT IS GENERALLY ADVISABLE FOR THE PARTICIPANT TO FILE 83(B) ELECTION.] DECIBEL THERAPEUTICS, INC. RESTRICTED STOCK AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN This Restricted Stock Agreement (the “Agreement”) is made this [] day of [], 20[ ], between Decibel Therapeutics, Inc., a Delaware corporation (the “Company”),

January 22, 2021 EX-10.26

Consulting Agreement, dated as of February 1, 2020, by and between the Registrant and Steven H. Holtzman

EX-10.26 Exhibit 10.26 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (together with its Schedule A, this “Agreement”) made as of February 1, 2020 (the “Effective Date”), is between Decibel Therapeutics, Inc., with a principal business address at 1325 Boylston St., Suite 500, Boston, MA 02215 USA (“Decibel”), and Steven H. Holtzman (“Consultant”). 1. Consulting Services. Whereas Consultant’s last

January 22, 2021 EX-10.23

Offer of Employment, dated as of October 12, 2016, by and between the Registrant and Ronald Vigliotta

EX-10.23 Exhibit 10.23 215 First street Cambridge, MA 02142 October 12, 20 I 6 Re: Offer of Employment Dear Ron: Decibel Therapeutics, Inc. (the “Company”) is pleased to confirm its offer to employ you as Senior Director, Finance reporting to Steve Holtzman, President & CEO. Your effective date of hire as an employee (the “Start Date”) shall be Monday, November 28, 2016 unless another date is agre

January 22, 2021 EX-10.21

Offer of Employment, dated as of September 9, 2020, by and between the Registrant and Elisabeth Leiderman, M.D.

EX-10.21 Exhibit 10.21 September 9, 2020 Re: Offer of Employment Dear Lis: Decibel Therapeutics, Inc. (the “Company”) is pleased to confirm its offer to employ you as Chief Financial Officer, reporting to Laurence Reid, Chief Executive Officer. 1. Date of Hire. Your effective date of hire as an employee (the “Start Date”) shall be no later than September 14, 2020 unless another date is agreed upon

January 22, 2021 EX-10.10

2021 Employee Stock Purchase Plan

EX-10.10 Exhibit 10.10 Decibel Therapeutics, Inc. 2021 EMPLOYEE STOCK PURCHASE PLAN The purpose of this 2021 Employee Stock Purchase Plan (this “Plan”) is to provide eligible employees of Decibel Therapeutics, Inc. (the “Company”) and certain of its subsidiaries with opportunities to purchase shares of the Company’s common stock, $0.001 par value per share (the “Common Stock”), commencing at such

January 22, 2021 EX-10.15

Lease, dated as of July 20, 2016, as amended, by and between Boylston West LLC and the Registrant

EX-10.15 Exhibit 10.15 Execution Version VAN NESS BOSTON, MASSACHUSETTS LEASE FROM BOYLSTON WEST LLC TO DECIBEL THERAPEUTICS, INC. TABLE OF CONTENTS ARTICLE I Basic Lease Provisions and Enumerations of Exhibits 1 1.1 Introduction 1 1.2 Basic Data 1 1.3 Enumeration of Exhibits 6 ARTICLE II Premises 7 2.1 Demise and Lease of Premises 7 2.2 Appurtenant Rights and Reservations 10 2.3 Tenant’s Right of

January 22, 2021 EX-10.19

Offer of Employment, dated as of June 17, 2016, by and between the Registrant and Steven H. Holtzman

EX-10.19 Exhibit 10.19 June 17, 2016 Re: Offer of Employment Dear Steve: Decibel Therapeutics, Inc. (the “Company”) is pleased to offer to employ you as Chief Executive Officer, reporting to the Company’s Board of Directors. Your effective date of hire as an employee will be July 5, 2016. For purposes of this offer letter, the actual first day of your employment shall be referred to as the “Start

January 22, 2021 EX-10.5

Form of Nonstatutory Stock Option Agreement under the 2015 Stock Incentive Plan

EX-10.5 Exhibit 10.5 DECIBEL THERAPEUTICS, INC. NONSTATUTORY STOCK OPTION AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN 1. Grant of Option. This Nonstatutory Stock Option Agreement (the “Agreement”) evidences the grant by Decibel Therapeutics, Inc. a Delaware corporation (the “Company”), on [ , 20] (the “Grant Date”) to [], an employee, consultant or director of the Company (the “Participant”)

January 22, 2021 EX-10.8

Form of Restricted Stock Unit Agreement under the 2021 Stock Incentive Plan

EX-10.8 Exhibit 10.8 Decibel Therapeutics, Inc. RESTRICTED STOCK UNIT AGREEMENT Decibel Therapeutics, Inc. (the “Company”) hereby grants the following restricted stock units pursuant to its 2021 Stock Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”): Grant Date: Number of restricted stock units (“RSUs”) granted:

January 22, 2021 EX-10.13

License Agreement, dated as of October 3, 2019, by and between the Regents of the University of California and the Registrant

EX-10.13 Exhibit 10.13 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. LICENSE AGREEMENT between THE REGENTS OF THE UNIVERSITY OF CALIFORNIA and Decibel Therapeutics for COMPOSITIONS AND METHODS FOR EXPRESSING OTOFERLIN UC Case

January 22, 2021 EX-10.11

License and Collaboration Agreement, dated as of November 15, 2017, as amended, by and between Regeneron Pharmaceuticals, Inc. and Decibel Therapeutics, Inc. (incorporated by reference to Exhibit 10.11 to the Registration Statement on Form S-1, File No. 333-252347, filed by Decibel Therapeutics, Inc. on January 22, 2021).

EX-10.11 Exhibit 10.11 Execution Version Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. LICENSE AND COLLABORATION AGREEMENT By and Between REGENERON PHARMACEUTICALS, INC. and DECIBEL THERAPEUTICS, INC. Dated as of November 15,

January 22, 2021 EX-10.20

Offer of Employment, dated as of August 11, 2016, by and between the Registrant and John Lee

EX-10.20 Exhibit 10.20 215 First Street Cambridge, MA 02142 August 11, 2016 Re: Offer of Employment Dear John: Decibel Therapeutics, Inc. (the “Company”) is pleased to confirm its offer to employ you as Senior Vice President, Pharmaceutical Development reporting to Steve Holtzman, President & CEO. Your effective date of hire as an employee (the “Start Date”) shall be no later than Tuesday, Septemb

January 22, 2021 EX-10.12

Standard Exclusive License Agreement, dated as of October 29, 2020, by and between the University of Florida Research Foundation, Incorporated and the Registrant

EX-10.12 Exhibit 10.12 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. STANDARD EXCLUSIVE LICENSE AGREEMENT UFRF Agreement No: [**] TABLE OF CONTENTS Section 1 Definitions Section 2 Grant Section 3 Diligence Obligations Section

January 22, 2021 EX-10.1

Form of Indemnification Agreement between the Registrant and each of its directors and executive officers

EX-10.1 Exhibit 10.1 INDEMNIFICATION AGREEMENT This Indemnification Agreement (“Agreement”) is made as of , 20 by and between Decibel Therapeutics, Inc., a Delaware corporation (the “Company”), and (“Indemnitee”). This Agreement supersedes and replaces any and all previous Agreements between the Company and Indemnitee covering the subject matter of this Agreement. [[Solely with respect to officers

January 22, 2021 EX-10.14

Exclusive License Agreement, dated as of August 26, 2019, by and between the Curators of the University of Missouri and the Registrant

EX-10.14 Exhibit 10.14 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. EXCLUSIVE LICENSE AGREEMENT THIS EXCLUSIVE LICENSE AGREEMENT (“AGREEMENT”) is made and entered into the date of last signature (“EFFECTIVE DATE”), by and be

January 22, 2021 EX-10.2

2015 Stock Incentive Plan, as amended

EX-10.2 Exhibit 10.2 2015 STOCK INCENTIVE PLAN OF DECIBEL THERAPEUTICS, INC. i TABLE OF CONTENTS Page 1. Purpose 1 2. Eligibility 1 3. Administration and Delegation 1 (a) Administration by the Board 1 (b) Appointment of Committees 1 4. Stock Available for Awards 2 (a) Number of Shares 2 (b) Substitute Awards 2 5. Stock Options 2 (a) General 2 (b) Incentive Stock Options 2 (c) Exercise Price 3 (d)

January 22, 2021 EX-3.4

Form of Amended and Restated Bylaws of the Registrant (to be effective upon the closing of this offering)

EX-3.4 Exhibit 3.4 AMENDED AND RESTATED BYLAWS OF DECIBEL THERAPEUTICS, INC. TABLE OF CONTENTS Page ARTICLE I STOCKHOLDERS 1 1.1 Place of Meetings 1 1.2 Annual Meeting 1 1.3 Special Meetings 1 1.4 Record Date for Stockholder Meetings 2 1.5 Notice of Meetings 2 1.6 Voting List 3 1.7 Quorum 3 1.8 Adjournments 4 1.9 Voting and Proxies 4 1.10 Action at Meeting 5 1.11 Nomination of Directors 5 1.12 Not

January 22, 2021 EX-3.1

Fourth Amended and Restated Certificate of Incorporation of the Registrant

EX-3.1 Exhibit 3.1 FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. (Pursuant to Sections 242 and 245 of the General Corporation Law of the State of Delaware) Decibel Therapeutics, Inc., a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the “General Corporation Law”), DOES HEREBY

January 22, 2021 EX-10.9

Form of Restricted Stock Agreement under the 2021 Stock Incentive Plan

EX-10.9 Exhibit 10.9 Decibel Therapeutics, Inc. RESTRICTED STOCK AGREEMENT Decibel Therapeutics, Inc. (the “Company”) hereby grants the following award of restricted stock pursuant to its 2021 Stock Incentive Plan. The terms and conditions attached hereto are also a part hereof. Notice of Grant Name of recipient (the “Participant”): Grant Date: Number of shares of the restricted common stock, $0.0

January 22, 2021 EX-10.6

2021 Stock Incentive Plan

EX-10.6 Exhibit 10.6 Decibel Therapeutics, Inc. 2021 STOCK INCENTIVE PLAN 1. Purpose The purpose of this 2021 Stock Incentive Plan (the “Plan”) of Decibel Therapeutics, Inc., a Delaware corporation (the “Company”), is to advance the interests of the Company’s stockholders by enhancing the Company’s ability to attract, retain and motivate persons who are expected to make important contributions to

January 22, 2021 EX-10.25

Sublease Agreement, dated June 20, 2019, by and between United HealthCare Services, Inc. and the Registrant

EX-10.25 Exhibit 10.25 SUBLEASE AGREEMENT THIS SUBLEASE AGREEMENT, dated June 20, 2019 (this “Sublease”), is entered into by and between United HealthCare Services, Inc., a Minnesota corporation (“Sublandlord”), and Decibel Therapeutics, Inc., a Delaware corporation (“Subtenant”). RECITALS WHEREAS, Boylston West LLC, as landlord (“Landlord”), and Sublandlord, as tenant, are parties to that certain

January 22, 2021 EX-10.18

Change in Control Agreement, dated as of November 2, 2020, by and between the Registrant and Laurence Reid, Ph.D.

EX-10.18 Exhibit 10.18 November 2, 2020 Laurence Reid Re: Decibel Therapeutics, Inc. Change in Control Agreement Dear Laurence: The Company desires to provide you with accelerated vesting of equity after a change in control (as defined herein) in certain circumstances. Accordingly, the Company agrees to provide a change in control benefit to you on the terms and conditions set forth in this Change

January 22, 2021 EX-10.16

Consulting Agreement, dated as of November 11, 2019, as amended, by and between the Registrant and Laurence Reid, Ph.D.

EX-10.16 Exhibit 10.16 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (together with its Schedule A, this “Agreement”) made as of November 11, 2019 (the “Effective Date”), is between Decibel Therapeutics, Inc., with a principal business address at 1325 Boylston St., Suite 500, Boston, MA 02215 USA (“Decibel”), and Laurence Reid, PhD (“Consultant”). 1. Consulting Services. Decibel hereby retains Co

January 22, 2021 EX-10.4

Form of Incentive Stock Option Agreement under the 2015 Stock Incentive Plan

EX-10.4 Exhibit 10.4 DECIBEL THERAPEUTICS, INC. INCENTIVE STOCK OPTION AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN 1. Grant of Option. This Incentive Stock Option Agreement (the “Agreement”) evidences the grant by Decibel Therapeutics, Inc. a Delaware corporation (the “Company”), on [ , 20] (the “Grant Date”) to [], an employee of the Company (the “Participant”), of an option to purchase, in

January 22, 2021 S-1

Power of Attorney (included on signature page)

S-1 Table of Contents As filed with the Securities and Exchange Commission on January 22, 2021 Registration No.

January 12, 2021 EX-10.13

material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. EXCLUSIVE LICENSE AGREEMENT

EX-10.13 Exhibit 10.13 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. EXCLUSIVE LICENSE AGREEMENT THIS EXCLUSIVE LICENSE AGREEMENT (“AGREEMENT”) is made and entered into the date of last signature (“EFFECTIVE DATE”), by and be

January 12, 2021 EX-10.27

CONSULTING AGREEMENT

EX-10.27 Exhibit 10.27 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (together with its Schedule A, this “Agreement”) made as of February 1, 2020 (the “Effective Date”), is between Decibel Therapeutics, Inc., with a principal business address at 1325 Boylston St., Suite 500, Boston, MA 02215 USA (“Decibel”), and Steven H. Holtzman (“Consultant”). 1. Consulting Services. Whereas Consultant’s last

January 12, 2021 DRS/A

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DRS/A Table of Contents As confidentially submitted to the Securities and Exchange Commission on January 12, 2021 as Amendment No.

January 12, 2021 DRSLTR

-

January 12, 2021 Stuart M. Falber By Electronic Submission +1 617 526 6663 (t) +1 617 526 5000 (f) wilmerhale.com U.S. Securities and Exchange Commission [email protected] Division of Corporation Finance 100 F Street, N.E. Washington, DC 20549 Attention: Jason Drory Re: Decibel Therapeutics, Inc. Draft Registration Statement on Form S-1 Submitted December 11, 2020 CIK No. 0001656536 Lad

December 11, 2020 EX-3.1

FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION DECIBEL THERAPEUTICS, INC. (Pursuant to Sections 242 and 245 of the General Corporation Law of the State of Delaware)

Exhibit 3.1 FOURTH AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF DECIBEL THERAPEUTICS, INC. (Pursuant to Sections 242 and 245 of the General Corporation Law of the State of Delaware) Decibel Therapeutics, Inc., a corporation organized and existing under and by virtue of the provisions of the General Corporation Law of the State of Delaware (the ?General Corporation Law?), DOES HEREBY CERTIF

December 11, 2020 EX-10.17

2

Exhibit 10.17 November 2, 2020 Laurence Reid Re: Decibel Therapeutics, Inc. Change in Control Agreement Dear Laurence: The Company desires to provide you with accelerated vesting of equity after a change in control (as defined herein) in certain circumstances. Accordingly, the Company agrees to provide a change in control benefit to you on the terms and conditions set forth in this Change in Contr

December 11, 2020 EX-10.11

STANDARD EXCLUSIVE LICENSE AGREEMENT UFRF Agreement No: [**] TABLE OF CONTENTS Section 1 Definitions Section 2 Grant Section 3 Diligence Obligations Section 4 Financial Consideration Section 5 Reports, Records and Accounting Section 6 Patent Prosecut

Exhibit 10.11 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. STANDARD EXCLUSIVE LICENSE AGREEMENT UFRF Agreement No: [**] TABLE OF CONTENTS Section 1 Definitions Section 2 Grant Section 3 Diligence Obligations Section 4 Financ

December 11, 2020 DRS

As confidentially submitted to the Securities and Exchange Commission on December 11, 2020

Table of Contents As confidentially submitted to the Securities and Exchange Commission on December 11, 2020 Registration No.

December 11, 2020 EX-10.22

2

Exhibit 10.22 September 9, 2020 Re: Offer of Employment Dear Lis: Decibel Therapeutics, Inc. (the ?Company?) is pleased to confirm its offer to employ you as Chief Financial Officer, reporting to Laurence Reid, Chief Executive Officer. 1. Date of Hire. Your effective date of hire as an employee (the ?Start Date?) shall be no later than September 14, 2020 unless another date is agreed upon by you a

December 11, 2020 EX-10.23

1325 Boylston Street • Suite 500, Boston, MA 02215

Exhibit 10.23 December 19, 2017 Re: Offer of Employment Dear Anna: Decibel Therapeutics, Inc. (the ?company?) is pleased to confirm its offer to employ you as Vice President, People, Community. and Culture reporting to Steve Holtzman. Chief Executive Officer. Your effective date of hire as an employee (the ?Start Date?) shall be no later than January 2, 2018 unless another date is agreed upon by y

December 11, 2020 EX-10.26

SUBLEASE AGREEMENT

Exhibit 10.26 SUBLEASE AGREEMENT THIS SUBLEASE AGREEMENT, dated June 20, 2019 (this ?Sublease?), is entered into by and between United HealthCare Services, Inc., a Minnesota corporation (?Sublandlord?), and Decibel Therapeutics, Inc., a Delaware corporation (?Subtenant?). RECITALS WHEREAS, Boylston West LLC, as landlord (?Landlord?), and Sublandlord, as tenant, are parties to that certain Lease, d

December 11, 2020 EX-10.5

DECIBEL THERAPEUTICS, INC. NONSTATUTORY STOCK OPTION AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN

Exhibit 10.5 DECIBEL THERAPEUTICS, INC. NONSTATUTORY STOCK OPTION AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN 1. Grant of Option. This Nonstatutory Stock Option Agreement (the ?Agreement?) evidences the grant by Decibel Therapeutics, Inc. a Delaware corporation (the ?Company?), on [ , 20] (the ?Grant Date?) to [], an employee, consultant or director of the Company (the ?Participant?), of an

December 11, 2020 EX-4.2

DECIBEL THERAPEUTICS, INC. THIRD AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT November 2, 2020

EX-4.2 4 filename4.htm Exhibit 4.2 Execution Version DECIBEL THERAPEUTICS, INC. THIRD AMENDED AND RESTATED INVESTORS’ RIGHTS AGREEMENT November 2, 2020 TABLE OF CONTENTS Page 1. Definitions. 1 2. Registration Rights. 5 2.1 Demand Registration. 5 2.2 Company Registration. 6 2.3 Underwriting Requirements. 7 2.4 Obligations of the Company. 8 2.5 Furnish Information. 9 2.6 Expenses of Registration. 10

December 11, 2020 EX-10.20

-2-

Exhibit 10.20 June 10, 2016 Re: Revised Offer of Employment - Final Dear Michael: Decibel Therapeutics, Inc. (the ?Company?) is pleased to offer to employ you as Chief Scientific Officer, reporting to the interim Chief Executive Officer, Kevin Starr. As you know, in the future a Chief Executive Officer will be hired by the Company and you will be an active participant in this recruiting process, a

December 11, 2020 EX-10.2

2015 STOCK INCENTIVE PLAN DECIBEL THERAPEUTICS, INC.

Exhibit 10.2 2015 STOCK INCENTIVE PLAN OF DECIBEL THERAPEUTICS, INC. i TABLE OF CONTENTS Page 1. Purpose 1 2. Eligibility 1 3. Administration and Delegation 1 (a) Administration by the Board 1 (b) Appointment of Committees 1 4. Stock Available for Awards 2 (a) Number of Shares 2 (b) Substitute Awards 2 5. Stock Options 2 (a) General 2 (b) Incentive Stock Options 2 (c) Exercise Price 3 (d) Duration

December 11, 2020 EX-10.16

2

Exhibit 10.16 October 28, 2020 Laurence Reid Re: Offer of Employment Dear Laurence: Decibel Therapeutics, Inc. (the ?Company?) is pleased to confirm its offer to employ you as Chief Executive Officer. 1. Date of Hire. Your effective date of hire as an employee (the ?Start Date?) shall be Monday, November 2, 2020 unless another date is agreed upon by you and the Company. 2. Compensation. Your regul

December 11, 2020 EX-10.19

215 First Street Cambridge, MA 02142

Exhibit 10.19 215 First Street Cambridge, MA 02142 August 5, 2016 Re: Offer of Employment Dear Paula: Decibel Therapeutics, Inc. (the ?Company?) is pleased to confirm its offer to employ you as Senior Vice President, Strategy, Portfolio and Program Leadership & Management reporting to Steve Holtzman, President & CEO. Your effective date of hire as an employee (the ?Start Date?) shall be no later t

December 11, 2020 EX-10.25

2

Exhibit 10.25 Name Address Re: Decibel Therapeutics, Inc. Change in Control Agreement Dear: The Company desires to provide you with accelerated vesting of equity in the event of termination after a change in control (as defined herein) in certain circumstances. Accordingly, the Company agrees to provide a change in control benefit to you on the terms and conditions set forth in this Change in Cont

December 11, 2020 EX-3.2

BY-LAWS HEARING, INC. (the “Corporation”)

Exhibit 3.2 BY-LAWS OF HEARING, INC. (the ?Corporation?) 1. Stockholders (a) Annual Meeting. The annual meeting of stockholders shall be held for the election of directors each year at such place, date and time as shall be designated by the Board of Directors. Any other proper business may be transacted at the annual meeting. If no date for the annual meeting is established or said meeting is not

December 11, 2020 EX-10.3

[NOTE: UNLESS THE SHARES ARE FULLY VESTED UPON GRANT, IT IS GENERALLY ADVISABLE FOR THE PARTICIPANT TO FILE 83(B) ELECTION.] DECIBEL THERAPEUTICS, INC. RESTRICTED STOCK AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN

Exhibit 10.3 [NOTE: UNLESS THE SHARES ARE FULLY VESTED UPON GRANT, IT IS GENERALLY ADVISABLE FOR THE PARTICIPANT TO FILE 83(B) ELECTION.] DECIBEL THERAPEUTICS, INC. RESTRICTED STOCK AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN This Restricted Stock Agreement (the ?Agreement?) is made this [] day of [], 20[ ], between Decibel Therapeutics, Inc., a Delaware corporation (the ?Company?), and [] (

December 11, 2020 EX-10.18

-2-

Exhibit 10.18 June 17, 2016 Re: Offer of Employment Dear Steve: Decibel Therapeutics, Inc. (the ?Company?) is pleased to offer to employ you as Chief Executive Officer, reporting to the Company?s Board of Directors. Your effective date of hire as an employee will be July 5, 2016. For purposes of this offer letter, the actual first day of your employment shall be referred to as the ?Start Date?. Yo

December 11, 2020 EX-21.1

SUBSIDIARIES OF THE REGISTRANT Name of subsidiary Jurisdiction of incorporation or organization Decibel Securities Corporation Massachusetts Decibel Therapeutics Australia Pty Ltd Australia

Exhibit 21.1 SUBSIDIARIES OF THE REGISTRANT Name of subsidiary Jurisdiction of incorporation or organization Decibel Securities Corporation Massachusetts Decibel Therapeutics Australia Pty Ltd Australia

December 11, 2020 EX-10.21

215 First Street Cambridge, MA 02142

Exhibit 10.21 215 First Street Cambridge, MA 02142 August 11, 2016 Re: Offer of Employment Dear John: Decibel Therapeutics, Inc. (the ?Company?) is pleased to confirm its offer to employ you as Senior Vice President, Pharmaceutical Development reporting to Steve Holtzman, President & CEO. Your effective date of hire as an employee (the ?Start Date?) shall be no later than Tuesday, September 6, 201

December 11, 2020 EX-10.13

material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. EXCLUSIVE LICENSE AGREEMENT

Exhibit 10.13 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. EXCLUSIVE LICENSE AGREEMENT THIS EXCLUSIVE LICENSE AGREEMENT (?AGREEMENT?) is made and entered into the date of last signature (?EFFECTIVE DATE?), by and between THE

December 11, 2020 EX-10.12

LICENSE AGREEMENT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA Decibel Therapeutics COMPOSITIONS AND METHODS FOR EXPRESSING OTOFERLIN UC Case No. [**]

Exhibit 10.12 Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. LICENSE AGREEMENT between THE REGENTS OF THE UNIVERSITY OF CALIFORNIA and Decibel Therapeutics for COMPOSITIONS AND METHODS FOR EXPRESSING OTOFERLIN UC Case No. [**]

December 11, 2020 EX-10.10

LICENSE AND COLLABORATION AGREEMENT By and Between REGENERON PHARMACEUTICALS, INC. DECIBEL THERAPEUTICS, INC. Dated as of November 15, 2017

Exhibit 10.10 Execution Version Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would likely cause competitive harm to the Company, if publicly disclosed. Double asterisks denote omissions. LICENSE AND COLLABORATION AGREEMENT By and Between REGENERON PHARMACEUTICALS, INC. and DECIBEL THERAPEUTICS, INC. Dated as of November 15, 2017 TAB

December 11, 2020 EX-10.24

215 First street Cambridge, MA 02142

Exhibit 10.24 215 First street Cambridge, MA 02142 October 12, 20 I 6 Re: Offer of Employment Dear Ron: Decibel Therapeutics, Inc. (the ?Company?) is pleased to confirm its offer to employ you as Senior Director, Finance reporting to Steve Holtzman, President & CEO. Your effective date of hire as an employee (the ?Start Date?) shall be Monday, November 28, 2016 unless another date is agreed upon b

December 11, 2020 EX-10.4

DECIBEL THERAPEUTICS, INC. INCENTIVE STOCK OPTION AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN

Exhibit 10.4 DECIBEL THERAPEUTICS, INC. INCENTIVE STOCK OPTION AGREEMENT GRANTED UNDER 2015 STOCK INCENTIVE PLAN 1. Grant of Option. This Incentive Stock Option Agreement (the ?Agreement?) evidences the grant by Decibel Therapeutics, Inc. a Delaware corporation (the ?Company?), on [ , 20] (the ?Grant Date?) to [], an employee of the Company (the ?Participant?), of an option to purchase, in whole o

December 11, 2020 EX-10.14

VAN NESS BOSTON, MASSACHUSETTS BOYLSTON WEST LLC DECIBEL THERAPEUTICS, INC.

Exhibit 10.14 Execution Version VAN NESS BOSTON, MASSACHUSETTS LEASE FROM BOYLSTON WEST LLC TO DECIBEL THERAPEUTICS, INC. TABLE OF CONTENTS ARTICLE I Basic Lease Provisions and Enumerations of Exhibits 1 1.1 Introduction 1 1.2 Basic Data 1 1.3 Enumeration of Exhibits 6 ARTICLE II Premises 7 2.1 Demise and Lease of Premises 7 2.2 Appurtenant Rights and Reservations 10 2.3 Tenant?s Right of First Of

December 11, 2020 EX-10.15

CONSULTING AGREEMENT

Exhibit 10.15 CONSULTING AGREEMENT THIS CONSULTING AGREEMENT (together with its Schedule A, this ?Agreement?) made as of November 11, 2019 (the ?Effective Date?), is between Decibel Therapeutics, Inc., with a principal business address at 1325 Boylston St., Suite 500, Boston, MA 02215 USA (?Decibel?), and Laurence Reid, PhD (?Consultant?). 1. Consulting Services. Decibel hereby retains Consultant

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